TFDP2 Antibody

Code CSB-PA623906LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: Mouse heart tissue, Hela whole cell lysate
    All lanes: TFDP2 antibody at 3.2μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000000 dilution
    Predicted band size: 50, 41, 42, 43, 40, 35, 47 kDa
    Observed band size: 50 kDa

  • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA623906LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA623906LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TFDP2 Polyclonal antibody
Uniprot No.
Target Names
TFDP2
Alternative Names
DP2 antibody; E2F dimerization partner 2 antibody; Tfdp2 antibody; TFDP2_HUMAN antibody; Transcription factor Dp 2 antibody; Transcription factor Dp-2 antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Transcription factor Dp-2 protein (344-386AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The TFDP2 Antibody (Product code: CSB-PA623906LA01HU) is Non-conjugated. For TFDP2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA623906LB01HU TFDP2 Antibody, HRP conjugated ELISA
FITC CSB-PA623906LC01HU TFDP2 Antibody, FITC conjugated
Biotin CSB-PA623906LD01HU TFDP2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The TFDP2:E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters.
Gene References into Functions
  1. GAB2, GSPT1, TFDP2 and ZFPM1 are four new susceptibility loci for testicular germ cell tumor. PMID: 26503584
  2. DP2 is expressed by the bronchial epithelium, and its activation drives epithelial differentiation, suggesting that in addition to its well-characterized role in inflammatory cell migration, DP2 might contribute to airway remodeling in asthmatic patients. PMID: 25312757
  3. This study demonstrates translation from an internal methionine. PMID: 8755520
Subcellular Location
Nucleus.
Protein Families
E2F/DP family
Tissue Specificity
High levels in heart and skeletal muscle. Also found in placenta, kidney, brain, lung and liver. The presence as well as the abundance of the different transcripts appear to vary significantly in different tissues and cell lines.
Database Links

HGNC: 11751

OMIM: 602160

KEGG: hsa:7029

STRING: 9606.ENSP00000420616

UniGene: Hs.379018

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