THRSP Antibody

Code CSB-PA846095LA01HU
Size US$299Purchase it in Cusabio online store
(only available for customers from the US)
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  • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA846095LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA846095LA01HU at dilution of 1:100

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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) THRSP Polyclonal antibody
Uniprot No. Q92748
Target Names THRSP
Alternative Names Lpgp antibody; LPGP1 antibody; MGC21659 antibody; OTTHUMP00000233866 antibody; S14 antibody; S14 protein antibody; SPOT 14 antibody; Spot 14 protein antibody; SPOT14 antibody; SPOT14 homolog antibody; Thrsp antibody; THRSP_HUMAN antibody; Thyroid hormone inducible hepatic protein antibody; Thyroid hormone responsive (SPOT14 homolog rat) antibody; Thyroid hormone responsive antibody; Thyroid hormone responsive protein antibody; Thyroid hormone responsive SPOT14 antibody; Thyroid hormone-inducible hepatic protein antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Thyroid hormone-inducible hepatic protein (41-144AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form Liquid
Tested Applications ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Data

Function Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA (By similarity). May function as transcriptional coactivator. May modulate the transcription factor activity of THRB.
Gene References into Functions
  1. The results of the present study indicated that Spot14/S14R were differently expressed in MSC adipogenesis in AIS patients, and they may be important in the abnormal adipogenic differentiation in AIS. PMID: 27082501
  2. In human breast cancer cell lines, S14 expression was highest in those representing the luminal subtype compared to those cell lines with basal characteristics. PMID: 25472762
  3. N-terminally truncated human Thrsp and its selenomethionyl derivative were collected to 4.0, 3.0 and 3.6 A resolution PMID: 21821901
  4. significantly greater thyroid hormone response for the human promoter, compared with the rat. PMID: 12960053
  5. human Spot 14 protein might regulate the p53 target gene, p21(WAF1/Cip1), via its direct interaction with the thyroid receptor or other p53 coactivators, such as Zac1. PMID: 18299245

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Subcellular Location Nucleus, Cytoplasm
Protein Families SPOT14 family
Tissue Specificity Mainly expressed in tissues that synthesize triglycerides.
Database Links

HGNC: 11800

OMIM: 601926

KEGG: hsa:7069

STRING: 9606.ENSP00000281030

UniGene: Hs.591969

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