THRSP Antibody

Datasheet

Code	CSB-PA846095ESR1HU
Size	US$166
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Image	Western blot All lanes: THRSPantibody at 2.13μg/ml + K562 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 17 kDa Observed band size: 17 kDa Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA846095ESR1HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA846095ESR1HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) THRSP Polyclonal antibody

Uniprot No.

Q92748

Target Names

THRSP

Alternative Names

Lpgp antibody; LPGP1 antibody; MGC21659 antibody; OTTHUMP00000233866 antibody; S14 antibody; S14 protein antibody; SPOT 14 antibody; Spot 14 protein antibody; SPOT14 antibody; SPOT14 homolog antibody; Thrsp antibody; THRSP_HUMAN antibody; Thyroid hormone inducible hepatic protein antibody; Thyroid hormone responsive (SPOT14 homolog rat) antibody; Thyroid hormone responsive antibody; Thyroid hormone responsive protein antibody; Thyroid hormone responsive SPOT14 antibody; Thyroid hormone-inducible hepatic protein antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Thyroid hormone-inducible hepatic protein (1-146AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA. May function as transcriptional coactivator. May modulate the transcription factor activity of THRB.

Gene References into Functions

The results of the present study indicated that Spot14/S14R were differently expressed in MSC adipogenesis in AIS patients, and they may be important in the abnormal adipogenic differentiation in AIS. PMID: 27082501
In human breast cancer cell lines, S14 expression was highest in those representing the luminal subtype compared to those cell lines with basal characteristics. PMID: 25472762
N-terminally truncated human Thrsp and its selenomethionyl derivative were collected to 4.0, 3.0 and 3.6 A resolution PMID: 21821901
significantly greater thyroid hormone response for the human promoter, compared with the rat. PMID: 12960053
human Spot 14 protein might regulate the p53 target gene, p21(WAF1/Cip1), via its direct interaction with the thyroid receptor or other p53 coactivators, such as Zac1. PMID: 18299245

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Subcellular Location

Nucleus. Cytoplasm.

Protein Families

SPOT14 family

Tissue Specificity

Mainly expressed in tissues that synthesize triglycerides.

Database Links

HGNC: 11800

OMIM: 601926

KEGG: hsa:7069

STRING: 9606.ENSP00000281030

UniGene: Hs.591969

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Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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