TNFAIP1 Antibody

1. TNFAIP1 silence significantly increased the migrated and invaded cells compared to that in control, while these increases were abolished by miR-424 suppression. PMID: 28535539
2. CREB is a negative regulator of the TNFAIP1 gene. PMID: 26398148
3. TNFAIP1 plays an important role in mediating miR-15a dependent biological functions in osteosarcoma. PMID: 26261520
4. MiR-181a played a critical role in regulating pancreatic cancer growth and migration, likely interacting with TNFAIP1. PMID: 26152285
5. Results showed that the expression of TNFAIP1 protein was significantly increased in osteosarcoma tissues and associated with distant metastasis. PMID: 24969828
6. Expression of TNFAIP1 is regulated by the transcriptional factor Sp1. PMID: 23912453
7. TNFAIP1 inhibited the transcriptional activities of nuclear factor kappa B (NF-kappaB) and activating protein-1 reporters PMID: 22810651
8. CK2 could phosphorylate TNFAIP1 in vitro and in vivo, which facilitated the distribution of TNFAIP1 in nucleus and enhanced its interaction with PCNA. PMID: 19851886
9. The promoter region of human TNFAIP1 gene was functionally characterized. PMID: 19593659
10. suggest that the TNFAIP1/POLDIP2 complex sense-antisense architecture represents a clinically significant transcriptional structural-functional gene module associated with amplification of the genomic region on 17q11.2 in breast cancer. PMID: 20158880
11. TNFAIP1 shows increased transcript levels in Alzheimer's disease brains PMID: 12600716
12. Expression levels of TNFAIP1 are high in COS7 and NIH3T3 cell lines but low in the cancer cell lines. PMID: 16870576

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HGNC: 11894

OMIM: 191161

KEGG: hsa:7126

STRING: 9606.ENSP00000226225

UniGene: Hs.76090