TPST1 Antibody

Code CSB-PA024132LA01HU
Size US$299 How to order?
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  • Western Blot
    Positive WB detected in: Rat liver tissue, Mouse liver tissue, Mouse kidney tissue
    All lanes: TPST1 antibody at 2.4μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 43 kDa
    Observed band size: 50 kDa

  • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA024132LA01HU at dilution of 1:100

  • Western Blot
    Positive WB detected in: HepG2 whole cell lysate, Hela whole cell lysate, SH-SY5Y whole cell lysate, U251 whole cell lysate, PC-3 whole cell lysate, 293 whole cell lysate, A549 whole cell lysate
    All lanes: TPST1 antibody at 1:2000
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 43 kDa
    Observed band size: 43 kDa

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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) TPST1 Polyclonal antibody
Uniprot No. O60507
Target Names TPST1
Alternative Names TPST1; Protein-tyrosine sulfotransferase 1; Tyrosylprotein sulfotransferase 1; TPST-1
Raised in Rabbit
Species Reactivity Human, Mouse, Rat
Immunogen Recombinant Human Protein-tyrosine sulfotransferase 1 protein (283-370AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated

The TPST1 Antibody (Product code: CSB-PA024132LA01HU) is Non-conjugated. For TPST1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA024132LB01HU TPST1 Antibody, HRP conjugated ELISA
FITC CSB-PA024132LC01HU TPST1 Antibody, FITC conjugated
Biotin CSB-PA024132LD01HU TPST1 Antibody, Biotin conjugated ELISA
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
Gene References into Functions
  1. TPST1 was significantly negatively correlated with the expression of cMet in lung cancer and may be a negative prognostic biomarker of lung cancer. PMID: 26238632
  2. TPST1 rs3757417T>G polymorphisms are associated with colorectal cancer. PMID: 25079514
  3. Affinity purified salivary TPST showed a single band of 50-54 kDa and is the first report characterizing a tyrosylprotein sulfotransferase in secretory fluid from the parotid gland PMID: 16244708
  4. results exclude TPST1 as the causative gene for Shwachman-Diamond syndrome PMID: 12032733
  5. Shear stress-dependent downregulation of TPST1 in human endothelium involves protein kinase C PMID: 12056800
  6. Human tyrosylprotein sulfotransferase may be functional as homodimer/oligomer in the trans-Golgi compartment. PMID: 16859706

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Subcellular Location Golgi apparatus membrane; Single-pass type II membrane protein.
Protein Families Protein sulfotransferase family
Tissue Specificity Ubiquitous. Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Database Links

HGNC: 12020

OMIM: 603125

KEGG: hsa:8460

STRING: 9606.ENSP00000302413

UniGene: Hs.421194

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