TRMT112 Antibody

Datasheet

Code	CSB-PA883416LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA883416LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human melanoma using CSB-PA883416LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) TRMT112 Polyclonal antibody

Uniprot No.

Q9UI30

Target Names

TRMT112

Alternative Names

TRMT112 antibody; AD-001 antibody; HSPC152 antibody; HSPC170 antibody; Multifunctional methyltransferase subunit TRM112-like protein antibody; tRNA methyltransferase 112 homolog antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human tRNA methyltransferase 112 homolog protein (1-125AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The TRMT112 Antibody (Product code: CSB-PA883416LA01HU) is Non-conjugated. For TRMT112 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA883416LB01HU	TRMT112 Antibody, HRP conjugated	ELISA
FITC	CSB-PA883416LC01HU	TRMT112 Antibody, FITC conjugated
Biotin	CSB-PA883416LD01HU	TRMT112 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Acts as an activator of both rRNA/tRNA and protein methyltransferases. Together with methyltransferase BUD23, methylates the N(7) position of a guanine in 18S rRNA. The heterodimer with HEMK2/N6AMT1 catalyzes N5-methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor. The heterodimer with HEMK2/N6AMT1 also monomethylates 'Lys-12' of histone H4 (H4K12me1). The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species. Involved in the pre-rRNA processing steps leading to small-subunit rRNA production. Together with methyltransferase METTL5, specifically methylates the 6th position of adenine in position 1832 of 18S rRNA.

Gene References into Functions

The localization of the TRMT112 protein is determined by WBSCR22, and the WBSCR22-TRMT112 complex is localized in the cell nucleus. PMID: 26214185

Subcellular Location

Nucleus, nucleoplasm. Cytoplasm, perinuclear region.

Protein Families

TRM112 family

Database Links

HGNC: 26940

KEGG: hsa:51504

STRING: 9606.ENSP00000438349

UniGene: Hs.333579

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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