Tmprss4 Antibody

Datasheet

Code	CSB-PA844988LA01MO
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Mus musculus (Mouse) Tmprss4 Polyclonal antibody

Uniprot No.

Q8VCA5

Target Names

Tmprss4

Alternative Names

Tmprss4 antibody; Cap2 antibody; Transmembrane protease serine 4 antibody; EC 3.4.21.- antibody; Channel-activating protease 2 antibody; mCAP2 antibody

Raised in

Rabbit

Species Reactivity

Mouse

Immunogen

Recombinant Mouse Transmembrane protease serine 4 protein (52-435AA)

Immunogen Species

Mus musculus (Mouse)

Conjugate

Non-conjugated

The Tmprss4 Antibody (Product code: CSB-PA844988LA01MO) is Non-conjugated. For Tmprss4 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA844988LB01MO	Tmprss4 Antibody, HRP conjugated	ELISA
FITC	CSB-PA844988LC01MO	Tmprss4 Antibody, FITC conjugated
Biotin	CSB-PA844988LD01MO	Tmprss4 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Plasma membrane-anchored serine protease that directly induces processing of pro-uPA/PLAU into the active form through proteolytic activity. Seems to be capable of activating ENaC.

Gene References into Functions

The lung fibrotic response evaluated at 28 days after bleomycin injury was markedly attenuated in the haplodeficient and deficient TMPRSS4 mice. PMID: 29529050
Epithelial Sodium Channel-Mediated Sodium Transport Is Not Dependent on the Membrane-Bound Serine Protease CAP2/Tmprss4 PMID: 26309024
Progression and metastatic potential of several cancers is concordant with an increased expression of TMPRSS4. PMID: 22944691
TMPRSS4 primarily activates ENaC by cleaving basic residues within the tract gammaK173-K186 distal to the furin cleavage site, thereby releasing a previously defined key inhibitory tract encompassing gammaR158-F168 from the gamma-subunit. PMID: 21993886

Subcellular Location

Cell membrane; Single-pass type II membrane protein.; [Transmembrane protease serine 4 catalytic chain]: Secreted.

Protein Families

Peptidase S1 family

Database Links

KEGG: mmu:214523

STRING: 10090.ENSMUSP00000034599

UniGene: Mm.436756

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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