Tmprss4 Antibody

Code CSB-PA844988LA01MO
Size US$166
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Product Details

Full Product Name
Rabbit anti-Mus musculus (Mouse) Tmprss4 Polyclonal antibody
Uniprot No.
Target Names
Tmprss4
Alternative Names
Tmprss4 antibody; Cap2 antibody; Transmembrane protease serine 4 antibody; EC 3.4.21.- antibody; Channel-activating protease 2 antibody; mCAP2 antibody
Raised in
Rabbit
Species Reactivity
Mouse
Immunogen
Recombinant Mouse Transmembrane protease serine 4 protein (52-435AA)
Immunogen Species
Mus musculus (Mouse)
Conjugate
Non-conjugated

The Tmprss4 Antibody (Product code: CSB-PA844988LA01MO) is Non-conjugated. For Tmprss4 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA844988LB01MO Tmprss4 Antibody, HRP conjugated ELISA
FITC CSB-PA844988LC01MO Tmprss4 Antibody, FITC conjugated
Biotin CSB-PA844988LD01MO Tmprss4 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
Plasma membrane-anchored serine protease that directly induces processing of pro-uPA/PLAU into the active form through proteolytic activity. Seems to be capable of activating ENaC.
Gene References into Functions
  1. The lung fibrotic response evaluated at 28 days after bleomycin injury was markedly attenuated in the haplodeficient and deficient TMPRSS4 mice. PMID: 29529050
  2. Epithelial Sodium Channel-Mediated Sodium Transport Is Not Dependent on the Membrane-Bound Serine Protease CAP2/Tmprss4 PMID: 26309024
  3. Progression and metastatic potential of several cancers is concordant with an increased expression of TMPRSS4. PMID: 22944691
  4. TMPRSS4 primarily activates ENaC by cleaving basic residues within the tract gammaK173-K186 distal to the furin cleavage site, thereby releasing a previously defined key inhibitory tract encompassing gammaR158-F168 from the gamma-subunit. PMID: 21993886
Subcellular Location
Cell membrane; Single-pass type II membrane protein.; [Transmembrane protease serine 4 catalytic chain]: Secreted.
Protein Families
Peptidase S1 family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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