UBE2Q2 Antibody

Datasheet

Code	CSB-PA845153HA01HU
Size	US$166
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Image	Western blot All lanes: UBE2Q2 antibody at 2µg/ml + A431 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 43, 37, 41, 39 kDa Observed band size: 43 kDa Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA845153HA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA845153HA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) UBE2Q2 Polyclonal antibody

Uniprot No.

Q8WVN8

Target Names

UBE2Q2

Alternative Names

LOC92912 antibody; UB2Q2_HUMAN antibody; UBE2Q2 antibody; Ubiquitin carrier protein Q2 antibody; Ubiquitin conjugating enzyme E2Q 2 antibody; Ubiquitin conjugating enzyme E2Q family member 2 antibody; Ubiquitin-conjugating enzyme E2 Q2 antibody; ubiquitin-conjugating enzyme E2Q (putative) 2 antibody; Ubiquitin-protein ligase Q2 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Ubiquitin-conjugating enzyme E2 Q2 protein (1-375AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The UBE2Q2 Antibody (Product code: CSB-PA845153HA01HU) is Non-conjugated. For UBE2Q2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA845153HB01HU	UBE2Q2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA845153HC01HU	UBE2Q2 Antibody, FITC conjugated
Biotin	CSB-PA845153HD01HU	UBE2Q2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination.

Gene References into Functions

UBE2Q1 hypomethylation is associated with Colorectal Cancer. PMID: 26745068
The newly characterized human gene, UBE2Q2, may have implications for the pathogenesis of acute lymphoblastic leukemia. PMID: 22642244
In the 21 breast cancer cases investigated, a high increase in UBE2Q2 expression was found in 8 breast cancers (38.1%), a moderately increased UBE2Q2 expression was observed in 7 cases (33.3%), and no sig. changes were detected in 6 cases (28.6%). PMID: 20193842
Found high expression levels of UBE2Q2 in human head and neck carcinoma cell lines and cancer tissues; found the level of UBE2Q2 is decreased in cell lines and cancer tissues that have resistance to CDDP or docetaxel. PMID: 19723876
the novel LOC92912 gene is characterized. It is over-expressed in hypopharyngeal tumours. Its functions may be linked with the cytoskeleton; it may represent a new target for cancer therapeutics. PMID: 16300736
Inhibition of the UBE2Q2 protein causes cells to undergo a prolonged prophase arrest suggesting that UBE2Q2 normally functions to antagonize an early mitotic checkpoint. PMID: 17471241

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Subcellular Location

Cytoplasm.

Protein Families

Ubiquitin-conjugating enzyme family

Tissue Specificity

Detected in hypopharyngeal head and neck squamous cell carcinoma, in tumor masses and invasive epithelium.

Database Links

HGNC: 19248

OMIM: 612501

KEGG: hsa:92912

STRING: 9606.ENSP00000267938

UniGene: Hs.23033

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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