UBE3C Antibody, Biotin conjugated

1. miR-542-3p functioned as a tumor suppressor gene in regulating the epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma via targeting UBE3C. PMID: 28666208
2. UBE3C promotes melanoma progression, possibly by inducing epithelial-mesenchymal transition in melanoma cells PMID: 26894856
3. data reveal that high UBE3C expression contributes to glioma progression by ubiquitination and degradation of ANXA7, and thus presents a novel and promising target for glioma therapy. PMID: 26067607
4. these observations suggest that UBE3C plays an important role in RCC development and progression, and UBE3C may be a novel target for prevention and treatment of ccRCC. PMID: 25658088
5. UBE3C is a mutant candidate oncogene involved in tumor development and progression of hepatocellular carcinoma. PMID: 24425307
6. knockdown renders cells more susceptible to the Hsp90 inhibitor 17-AAG, suggesting that UBE3C protects against the harmful accumulation of protein fragments arising from incompletely degraded proteasome substrates. PMID: 24158444
7. Our findings provide evidence that variations in UBE3C are potent genetic markers of nasal polyps development in Korean asthmatics. PMID: 21881582
8. negatively regulates type I interferon through ubiquitination of the transcription factors PMID: 21167755
9. gene polymorphism is associated with the risk of Aspirin-intolerant asthma PMID: 20934631
10. TIP120B is a specific substrate of KIAA10; both are highly expressed in human skeletal muscle, suggesting that KIAA10 may regulate TIP120B homeostasis specifically in this tissue. PMID: 12692129

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HGNC: 16803

OMIM: 614454

KEGG: hsa:9690

STRING: 9606.ENSP00000309198

UniGene: Hs.118351