UNC5B Antibody, Biotin conjugated

1. Negative regulation of Naa10 towards NTN1 and its receptor UNC5B were also detected upon treatment of all-trans retinoid acid, which was often used to induce morphological differentiation. PMID: 27910960
2. These findings point to a new important function of UNC5B and provide a potential basis for hASCs-mediated bone regeneration. PMID: 29158083
3. Our results suggest that UNC5B overexpression inhibits the proliferation and migration of bladder cancer cells by inducing cell cycle arrest at G2/M phase. PMID: 27846823
4. UNC5B expression is decreased in bladder cancer cells compared to normal bladder cell lines. PMID: 24528886
5. Data indicate that dysregulation of expression of netrin-1 NTN1 in smooth muscle cell (SMC) and its chemorepulsive receptor UNC5B in macrophages are involved in the development of atherosclerosis and unstable plaques. PMID: 24122613
6. unc5b expression is greater in adipose tissue of obese versus lean subjects. PMID: 24584118
7. Higher netrin-1 and lower UNC5B expression in all prostate carcinoma cell lines indicated that netrin-1 and UNC5B could be used to predict metastasis. PMID: 23666553
8. Low UNC5B expression was an independent risk factor for postoperative recurrence in patients with different stages and grades bladder cancer. PMID: 23055195
9. UNC5B protein expressed in macrophages in hypoxic regions of atherosclerotic regions in human. PMID: 23599441
10. UNC5B was downregulated in kidney carcinoma. PMID: 23526078
11. Reducing Unc5b levels in Sip1 knockout slices and brains rescues cell migration in cortical interneurons. PMID: 23312517
12. Hypoxia-inducible factor 1 controls the expression of the uncoordinated-5-B receptor, but not of netrin-1, in first trimester human placenta PMID: 22252496
13. The mRNA expression analysis using tissue samples revealed that UNC5B mRNA was down-expressed in about 20% of CRC patients, and the patients with low-UNC5B-expression tumors showed a significantly higher recurrence rate after curative surgery. PMID: 21922135
14. Netrin-1 can promote the potential of proliferation and invasion of extravillous trophoblasts in vitro through its receptors neogenin and UNC5B. PMID: 19570425
15. Robo4 specifically binds to UNC5B, a vascular Netrin receptor, revealing unexpected interactions between two endothelial guidance receptors. PMID: 21238923
16. The recruitment of PP2A to UNC5H2/B allows the activation of DAPk via a PP2A-mediated dephosphorylation and that this mechanism is involved in angiogenesis regulation. PMID: 21172653
17. Down-regulation of UNC5b gene expression is related to angiogenesis of hepatocellular carcinoma. PMID: 20092749
18. UNC5B receptor is localized to villous and extravillous cytotrophoblasts proximal to anchoring areas during the first trimester. PMID: 19826074
19. Modulation of G(ialpha(2)) signaling by the axonal guidance of this protein PMID: 12359238
20. In this study, we show that Unc5B, a member of the netrin receptor family, interacts with neogenin as a coreceptor for RGMa. PMID: 19273616
21. Stronger expression of UNC5B and UNC5C receptors in synovial fibroblasts might contribute to the disordered phenotype of rheumatoid arthritis and osteoarthritis. PMID: 19822088

Show More

Hide All

HGNC: 12568

OMIM: 607870

KEGG: hsa:219699

STRING: 9606.ENSP00000334329

UniGene: Hs.522997