USP47 Antibody, Biotin conjugated

Datasheet

Code	CSB-PA856964LD01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) USP47 Polyclonal antibody

Uniprot No.

Q96K76

Target Names

USP47

Alternative Names

Deubiquitinating enzyme 47 antibody; TFRP antibody; Trf TATA binding protein related factor proximal homolog antibody; Trf TATA binding protein related factor proximal homolog Drosophila antibody; Ubiquitin carboxyl-terminal hydrolase 47 antibody; Ubiquitin specific peptidase 47 antibody; Ubiquitin specific processing protease 47 antibody; Ubiquitin specific protease 47 antibody; Ubiquitin thioesterase 47 antibody; Ubiquitin thiolesterase 47 antibody; Ubiquitin-specific-processing protease 47 antibody; UBP47_HUMAN antibody; USP47 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Ubiquitin carboxyl-terminal hydrolase 47 protein (1-157AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Biotin

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER). Acts as a regulator of cell growth and genome integrity. May also indirectly regulate CDC25A expression at a transcriptional level.

Gene References into Functions

these results suggest that USP47 may play distinct roles in ubiquitin-mediated cellular processes via de-ubiquitinating enzymes activity. PMID: 26115687
miR-204-5p acts as a tumor suppressor in gastric cancer through inhibiting USP47 and RAB22A. PMID: 25429829
USP47 is a deubiquitinase that prevents beta-catenin ubiquitination. PMID: 26169834
Data indicate that E-cadherin ubiquitination consistently increases after depletion of kinesin-like protein KIFC3 or ubiquitin-specific protease USP47. PMID: 25253721
The results of this study indicated that USP47 plays a crucial role in the control of axonal growth during neuronal development by antagonizing CHIP-mediated katanin-p60 degradation. PMID: 23904609
USP47 has a role in regulating DNA repair and maintaining genome integrity PMID: 21362556
USP47, a novel beta-Trcp interactor, regulates cell growth and survival, potentially providing a novel target for anticancer therapies. PMID: 19966869

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Subcellular Location

Cytoplasm.

Protein Families

Peptidase C19 family

Tissue Specificity

Expressed in skeletal muscle, heart and testis.

Database Links

HGNC: 20076

OMIM: 614460

KEGG: hsa:55031

STRING: 9606.ENSP00000339957

UniGene: Hs.577256

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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