VTI1B Antibody

Datasheet

Code	CSB-PA887014LA01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) VTI1B Polyclonal antibody

Uniprot No.

Q9UEU0

Target Names

VTI1B

Alternative Names

HGNC:17793 antibody; V SNARE antibody; v-SNARE antibody; Vesicle associated soluble NSF attachment protein receptor antibody; Vesicle transport through interaction with t SNAREs 1B antibody; Vesicle transport through interaction with t SNAREs homolog 1B (yeast) antibody; Vesicle transport through interaction with t-SNAREs homolog 1B antibody; Vesicle transport v-SNARE protein Vti1-like 1 antibody; VTI1 antibody; VTI1 like antibody; Vti1 rp1 antibody; VTI1-LIKE antibody; Vti1-rp1 antibody; VTI1B antibody; VTI1B_HUMAN antibody; VTI1L antibody; VTI1L1 antibody; VTI2 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Vesicle transport through interaction with t-SNAREs homolog 1B protein (2-208AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The VTI1B Antibody (Product code: CSB-PA887014LA01HU) is Non-conjugated. For VTI1B Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA887014LB01HU	VTI1B Antibody, HRP conjugated	ELISA
FITC	CSB-PA887014LC01HU	VTI1B Antibody, FITC conjugated
Biotin	CSB-PA887014LD01HU	VTI1B Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.

Gene References into Functions

Vti1b-dependent tethering of Lytic granule and CD3-endo determines accumulation, docking, and efficient lytic granule secretion at the immunological synapse. PMID: 21562157
Results suggest that the combinational SNARE proteins VAMP8 and Vti1b mediate the fusion of antimicrobial and canonical autophagosomes with lysosomes, an essential event for autophagic degradation. PMID: 20089838
A dual mechanism controlling the localization and function of exocytic v-SNAREs. PMID: 12853575
Ca(2+) dissociates the Hrs-containing complex but not the VAMP-2-containing SNARE complex PMID: 14769786
epsin 4 epsin-related protein is an adaptor for vti1b PMID: 15371541
Results report that syntaxin 7, syntaxin 8, vti1b and VAMP8 physically and functionally interact with CFTR. PMID: 18570918

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Subcellular Location

Early endosome membrane; Single-pass type IV membrane protein. Late endosome membrane; Single-pass type IV membrane protein. Lysosome membrane. Cytoplasmic granule. Recycling endosome membrane; Single-pass type IV membrane protein.

Protein Families

VTI1 family

Tissue Specificity

Expressed in all tissues examined.

Database Links

HGNC: 17793

OMIM: 603207

KEGG: hsa:10490

STRING: 9606.ENSP00000450731

UniGene: Hs.741177

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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