WBP11 Antibody

Code CSB-PA025975GA01HU
Size $600
Order now
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Uniprot No.
Target Names
WBP11
Alternative Names
DKFZp779M1063 antibody; MGC94547 antibody; Npw38 binding protein antibody; Npw38 binding protein NpwBP antibody; Npw38-binding protein antibody; NpwBP antibody; PPP1R165 antibody; Protein phosphatase 1 regulatory subunit 165 antibody; SH3 domain binding protein SNP70 antibody; SH3 domain-binding protein SNP70 antibody; SIPP1 antibody; SNP70 antibody; Splicing factor PQBP1 and PP1 interacting antibody; Splicing factor that interacts with PQBP 1 and PP1 antibody; Splicing factor that interacts with PQBP-1 and PP1 antibody; WBP 11 antibody; WBP-11 antibody; Wbp11 antibody; WBP11_HUMAN antibody; WW domain binding protein 11 antibody; WW domain-binding protein 11 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human WBP11
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Activates pre-mRNA splicing. May inhibit PP1 phosphatase activity.
Gene References into Functions
  1. The WW domain belonging to polyglutamine tract-binding protein 1 (PQBP1) is of particular interest due to its direct involvement in several X chromosome-linked intellectual disabilities, including Golabi-Ito-Hall (GIH) syndrome, where a single point mutation (Y65C) correlates with the development of the disease. The mutant cannot bind to its natural ligand WBP11, which regulates mRNA processing PMID: 27456546
  2. SIPP1 is a positive regulator of pre-mRNA splicing that is regulated by nucleocytoplasmic shuttling PMID: 16162498
Subcellular Location
Nucleus. Cytoplasm. Note=Predominantly located in the nucleus with granular heterogeneous distribution. Excluded from nucleoli in interphase cells, distributed throughout cytoplasm in dividing cells. Colocalized with SC35 and U2B in the nucleus. In the cytoplasm, associates with the intermediate filament protein vimentin.
Tissue Specificity
Ubiquitous. Highly expressed in the heart, pancreas, kidney skeletal muscle, placenta and brain (at protein level). Weakly expressed in liver and lung.
Database Links

HGNC: 16461

KEGG: hsa:51729

STRING: 9606.ENSP00000261167

UniGene: Hs.655138

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
webinars: DT3C facilitates antibody internalization X
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*