WIZ Antibody

Datasheet

Code	CSB-PA026123LA01HU
Size	US$166
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Image	IHC image of CSB-PA026123LA01HU diluted at 1:200 and staining in paraffin-embedded human glioma performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) WIZ Polyclonal antibody

Uniprot No.

O95785

Target Names

WIZ

Alternative Names

Protein Wiz antibody; Widely interspaced zinc finger containing protein antibody; Widely-interspaced zinc finger-containing protein antibody; Wiz antibody; WIZ zinc finger antibody; WIZ_HUMAN antibody; Zinc finger protein 803 antibody; ZNF803 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Protein Wiz protein (1469-1574AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The WIZ Antibody (Product code: CSB-PA026123LA01HU) is Non-conjugated. For WIZ Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA026123LB01HU	WIZ Antibody, HRP conjugated	ELISA
FITC	CSB-PA026123LC01HU	WIZ Antibody, FITC conjugated
Biotin	CSB-PA026123LD01HU	WIZ Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:200-1:500

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

May link EHMT1 and EHMT2 histone methyltransferases to the CTBP corepressor machinery. May be involved in EHMT1-EHMT2 heterodimer formation and stabilization.

Gene References into Functions

Disrupting the association of G9a-GLP with chromatin by depleting WIZ resulted in altered gene expression and protein-protein interactions that were distinguishable from that of small molecule-based inhibition of G9a/GLP PMID: 26338712
Data indicate zinc finger proteins ZNF644 and WIZ as two core subunits in the histone-lysine N-methyltransferase G9a/GLP complex, and interact with the transcription activation domain of G9a and GLP. PMID: 25789554

Subcellular Location

Nucleus.

Protein Families

Krueppel C2H2-type zinc-finger protein family

Database Links

HGNC: 30917

KEGG: hsa:58525

STRING: 9606.ENSP00000263381

UniGene: Hs.442138

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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Target Therapy

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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