WIZ Antibody

Code CSB-PA026123LA01HU
Size US$166
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Image
  • IHC image of CSB-PA026123LA01HU diluted at 1:200 and staining in paraffin-embedded human glioma performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) WIZ Polyclonal antibody
Uniprot No.
Target Names
WIZ
Alternative Names
Protein Wiz antibody; Widely interspaced zinc finger containing protein antibody; Widely-interspaced zinc finger-containing protein antibody; Wiz antibody; WIZ zinc finger antibody; WIZ_HUMAN antibody; Zinc finger protein 803 antibody; ZNF803 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Protein Wiz protein (1469-1574AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The WIZ Antibody (Product code: CSB-PA026123LA01HU) is Non-conjugated. For WIZ Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA026123LB01HU WIZ Antibody, HRP conjugated ELISA
FITC CSB-PA026123LC01HU WIZ Antibody, FITC conjugated
Biotin CSB-PA026123LD01HU WIZ Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:200-1:500
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May link EHMT1 and EHMT2 histone methyltransferases to the CTBP corepressor machinery. May be involved in EHMT1-EHMT2 heterodimer formation and stabilization.
Gene References into Functions
  1. Disrupting the association of G9a-GLP with chromatin by depleting WIZ resulted in altered gene expression and protein-protein interactions that were distinguishable from that of small molecule-based inhibition of G9a/GLP PMID: 26338712
  2. Data indicate zinc finger proteins ZNF644 and WIZ as two core subunits in the histone-lysine N-methyltransferase G9a/GLP complex, and interact with the transcription activation domain of G9a and GLP. PMID: 25789554
Subcellular Location
Nucleus.
Protein Families
Krueppel C2H2-type zinc-finger protein family
Database Links

HGNC: 30917

KEGG: hsa:58525

STRING: 9606.ENSP00000263381

UniGene: Hs.442138

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