ZDHHC5 Antibody

Code CSB-PA861196LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA861196LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA861196LA01HU at dilution of 1:100

  • Immunofluorescent analysis of 293T cells using CSB-PA861196LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ZDHHC5 Polyclonal antibody
Uniprot No.
Target Names
ZDHHC5
Alternative Names
ZDHHC5; KIAA1748; ZNF375; Palmitoyltransferase ZDHHC5; Zinc finger DHHC domain-containing protein 5; DHHC-5; Zinc finger protein 375
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Palmitoyltransferase ZDHHC5 protein (231-500AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The ZDHHC5 Antibody (Product code: CSB-PA861196LA01HU) is Non-conjugated. For ZDHHC5 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA861196LB01HU ZDHHC5 Antibody, HRP conjugated ELISA
FITC CSB-PA861196LC01HU ZDHHC5 Antibody, FITC conjugated
Biotin CSB-PA861196LD01HU ZDHHC5 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates and is involved in a variety of cellular processes. Palmitoylates the G-protein coupled receptor SSTR5 and for FLOT2.
Gene References into Functions
  1. High ZDHHC5 expression is associated with Glioma. PMID: 28775165
  2. Data indicate that DHHC5 has oncogenic capacity and contributes to tumor formation in non-small cell lung cancer. PMID: 25573953
  3. ZDHHC5 and SSTR5 are colocalized at the plasma membrane and coexpression of ZDHHC5 increased palmitoylation of SSTR5 whereas knock-down of endogenous ZDHHC5 by siRNAs decreased it. PMID: 21820437
  4. Data show that palmitoyl acyltransferases DHHC5, DHHC6, and DHHC8 appear to be S-acylated on three cysteine residues within a novel CCX(7-13)C(S/T) motif downstream of a conserved Asp-His-His-Cys cysteine-rich domain. PMID: 19801377
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
DHHC palmitoyltransferase family, ERF2/ZDHHC9 subfamily
Database Links

HGNC: 18472

OMIM: 614586

KEGG: hsa:25921

STRING: 9606.ENSP00000287169

UniGene: Hs.27239

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