rgpB Antibody

Code CSB-PA310587LA01EYA
Size US$166
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Product Details

Full Product Name
Rabbit anti-Porphyromonas gingivalis rgpB Polyclonal antibody
Uniprot No.
Target Names
rgpB
Alternative Names
rgpB antibody; prtRII antibody; rgp2 antibody; PG_0506Gingipain R2 antibody; EC 3.4.22.37 antibody; Arg-gingipain antibody; Gingipain 2 antibody; RGP-2 antibody
Raised in
Rabbit
Species Reactivity
Porphyromonas gingivalis
Immunogen
Recombinant Porphyromonas gingivalis Gingipain R2 protein (230-473AA)
Immunogen Species
Porphyromonas gingivalis
Conjugate
Non-conjugated

The rgpB Antibody (Product code: CSB-PA310587LA01EYA) is Non-conjugated. For rgpB Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA310587LB01EYA rgpB Antibody, HRP conjugated ELISA
FITC CSB-PA310587LC01EYA rgpB Antibody, FITC conjugated
Biotin CSB-PA310587LD01EYA rgpB Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Description

The rgpB polyclonal antibody is produced by injecting rabbits with the recombinant Porphyromonas gingivalis Gingipain R2 protein (230-473aa), which serves as the immunogen. The rabbits then produce antibodies against the Porphyromonas gingivalis rgpB antigen. These antibodies are purified from the rabbit serum using protein G purification. The purity is 95%+. The resulting purified rabbit anti-Porphyromonas gingivalis rgpB polyclonal antibody is highly specific to Porphyromonas gingivalis rgpB and has a high affinity for the antigen. This rgpB antibody is suitable for use in ELISA.

The rgpB protein mainly degrades and modifies host proteins, particularly those involved in the immune response, to facilitate the survival of P. gingivalis within the host. It also plays a role in the regulation of gene expression in P. gingivalis and the induction of tissue destruction and bone resorption associated with periodontitis.

Customer Reviews and Q&A

 Customer Reviews
Average Rating:
5.0 - 1 reviews

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Applications : western blot

Sample type: cells

Review: Rgp-specific and Kgp-specific proteolytic activities were determined in whole P. gingivalis cultures grown for 24 h in iron- and heme-rich conditions (Hm) or in iron_x005fand heme-free conditions (DIP).

By Anonymous

Target Background

Function
Thiol protease. Acts synergistically with RgpA to catalyze the maturation of fimbrial subunits, such as FimA. Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defense mechanisms.
Subcellular Location
Secreted.
Protein Families
Peptidase C25 family
Database Links

KEGG: pgi:PG_0506

STRING: 242619.PG0506

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