rtcB Antibody, HRP conjugated

Code CSB-PA341647YB01EVN
Size US$166
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Product Details

Full Product Name
Rabbit anti-Escherichia coli (strain K12) rtcB Polyclonal antibody
Uniprot No.
Target Names
rtcB
Alternative Names
rtcB antibody; yhgL antibody; b3421 antibody; JW3384 antibody; RNA-splicing ligase RtcB antibody; EC 6.5.1.8 antibody; 3'-phosphate/5'-hydroxy nucleic acid ligase antibody
Raised in
Rabbit
Species Reactivity
Escherichia coli
Immunogen
Recombinant Escherichia coli RNA-splicing ligase RtcB protein (1-408AA)
Immunogen Species
Escherichia coli (strain K12)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
GTP-dependent RNA ligase that is involved in tRNA splicing and RNA repair. Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends. Also acts as a DNA ligase in case of DNA damage by splicing 'dirty' DNA breaks, characterized by 3'-phosphate (or cyclic-phosphate) and 5'-hydroxy ends that cannot be sealed by classical DNA ligases.
Gene References into Functions
  1. our findings not only provide a physiological function for the RNA ligase RtcB in bacteria but highlight the reversibility of ribosome heterogeneity, a crucial but hitherto undescribed concept for translational regulation. PMID: 27789694
  2. Data show that RtcB seals broken RNAs with 3'-phosphate and 5'-OH ends. PMID: 22474365
  3. RtcB, a novel RNA ligase, can catalyze tRNA splicing and HAC1 mRNA splicing in vivo PMID: 21757685
Protein Families
RtcB family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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