Recombinant Bovine Fatty acid-binding protein, heart (FABP3)

Code CSB-YP007943BO
MSDS
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Source Yeast
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Code CSB-EP007943BO
MSDS
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Source E.coli
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Code CSB-EP007943BO-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP007943BO
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP007943BO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
FABP3
Uniprot No.
Alternative Names
FABP3Fatty acid-binding protein; heart; Fatty acid-binding protein 3; Heart-type fatty acid-binding protein; H-FABP; Mammary-derived growth inhibitor; MDGI
Species
Bos taurus (Bovine)
Expression Region
2-133
Target Protein Sequence
VDAFVGTWK LVDSKNFDDY MKSLGVGFAT RQVGNMTKPT TIIEVNGDTV IIKTQSTFKN TEISFKLGVE FDETTADDRK VKSIVTLDGG KLVHVQKWNG QETSLVREMV DGKLILTLTH GTAVCTRTYE KQA
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.; MDGI reversibly inhibits proliferation of mammary carcinoma cells.
Gene References into Functions
  1. Sequence analysis showed that many transcriptional factor binding sites including TATA-box and CCAAT-box were present on the 5'-flanking region of bovine FABP3, and four CpG islands were found on nucleotides from -891 to +118. PMID: 27270359
  2. FABP3 has a role in milk fat synthesis signaling. PMID: 24947174
  3. FABP3 gene frequency and SNP genotypes in Holstein-Friesian cows and its relationship with protein and fat content in milk PMID: 25474885
  4. Thus, the results of our study suggest that the H-FABP and PSMC1 gene polymorphisms could be used as genetic markers in marker-assisted selection for improving Qinchuan beef cattle PMID: 24668675
  5. polymorphisms can be used to select for milk with lower concentrations of saturated fatty acids and higher concentrations of unsaturated fatty acids PMID: 23831098
  6. MRF4 and H-FABP genes are associated with growth traits in Qinchuan cattle and related hybrids PMID: 20582633
  7. fine mapping of this gene to BTA2q45 by fluorescence in situ hybridization and radiation hybrid mapping PMID: 14687081
  8. The results of this study suggest that suggest that SLC27A6, ACSL1, FABP3, AGPAT6, and LPIN1 coordinately regulate the channeling of fatty acids toward copious milk fat synthesis in bovine mammary. PMID: 18492828

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Subcellular Location
Cytoplasm. Mitochondrion matrix.
Protein Families
Calycin superfamily, Fatty-acid binding protein (FABP) family
Tissue Specificity
Mammary epithelial cells of developing lobuloalveolar structures and heart.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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