Recombinant Chicken Mothers against decapentaplegic homolog 6(SMAD6)

Product Type Recombinant Protein
Uniprot No. Q9W734
Abbreviation SMAD6
Species Gallus gallus (Chicken)
Gene Names SMAD6
Protein Names Recommended name: Mothers against decapentaplegic homolog 6 Short name= MAD homolog 6 Short name= Mothers against DPP homolog 6 Alternative name(s): SMAD family member 6 Short name= SMAD 6 Short name= Smad6
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Function Acts as a mediator of TGF-beta and BMP antiflammatory activity. Suppresses IL1R-TLR signaling, preventing NF-kappa-B activation, and BMP-SMAD1 signaling pathway. Binds to regulatory elements in target promoter regions (By similarity).
Subcellular Location Nucleus
Protein Families Dwarfin/SMAD family
Tissue Specificity Developing heart, eyes and limbs.
Database Links

UniGene: Gga.3878

Pathway TGF-beta signaling pathway

Product Details for Different Expression Systems

Product Name Recombinant Chicken Mothers against decapentaplegic homolog 6(SMAD6),Yeast
Code CSB-YP892952CH
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MFRSKRSGLV RRLWRSRVIP ERDGGDGNGQ SSERNATAVT AEGQRMAQPR RAQEGEGRPV RCCLFAERPG PELPPPPPPP PPGGASPPGP GGGEARSRLV LLERELKAVT YALLKRLKER SLHSLLQAVE SRGGTPGGCV LVARGELRLG AARRPPPHLL LGKLFRWPDL QHPAELKALC ECQSFGAADG PTVCCNPYHF SRLCGPESPP PPYSRLSPND EQKPLDLSDS TLSYTETEAT NSPNVTPGEF SDASTSPDAV KRSHWCNVAY WEHRTRVGRL YTVYEQSVSI FYDLPQGNGF CLGQLNLENR SETVRRTRSK IGYGILLSKE PDGVWAYNRS EHPIFVNSPT LDIPNCRTLI VRKVMPGYSI KVFDYEKSCL LQHTAELDYA DGPYDPNSVR ISFAKGWGPC YSRQFITSCP CWLEILLSNN R
Expression Region 1-431
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
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Product Name Recombinant Chicken Mothers against decapentaplegic homolog 6(SMAD6),E.coli
Code CSB-EP892952CH
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MFRSKRSGLV RRLWRSRVIP ERDGGDGNGQ SSERNATAVT AEGQRMAQPR RAQEGEGRPV RCCLFAERPG PELPPPPPPP PPGGASPPGP GGGEARSRLV LLERELKAVT YALLKRLKER SLHSLLQAVE SRGGTPGGCV LVARGELRLG AARRPPPHLL LGKLFRWPDL QHPAELKALC ECQSFGAADG PTVCCNPYHF SRLCGPESPP PPYSRLSPND EQKPLDLSDS TLSYTETEAT NSPNVTPGEF SDASTSPDAV KRSHWCNVAY WEHRTRVGRL YTVYEQSVSI FYDLPQGNGF CLGQLNLENR SETVRRTRSK IGYGILLSKE PDGVWAYNRS EHPIFVNSPT LDIPNCRTLI VRKVMPGYSI KVFDYEKSCL LQHTAELDYA DGPYDPNSVR ISFAKGWGPC YSRQFITSCP CWLEILLSNN R
Expression Region 1-431
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Chicken Mothers against decapentaplegic homolog 6(SMAD6),Baculovirus
Code CSB-BP892952CH
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MFRSKRSGLV RRLWRSRVIP ERDGGDGNGQ SSERNATAVT AEGQRMAQPR RAQEGEGRPV RCCLFAERPG PELPPPPPPP PPGGASPPGP GGGEARSRLV LLERELKAVT YALLKRLKER SLHSLLQAVE SRGGTPGGCV LVARGELRLG AARRPPPHLL LGKLFRWPDL QHPAELKALC ECQSFGAADG PTVCCNPYHF SRLCGPESPP PPYSRLSPND EQKPLDLSDS TLSYTETEAT NSPNVTPGEF SDASTSPDAV KRSHWCNVAY WEHRTRVGRL YTVYEQSVSI FYDLPQGNGF CLGQLNLENR SETVRRTRSK IGYGILLSKE PDGVWAYNRS EHPIFVNSPT LDIPNCRTLI VRKVMPGYSI KVFDYEKSCL LQHTAELDYA DGPYDPNSVR ISFAKGWGPC YSRQFITSCP CWLEILLSNN R
Expression Region 1-431
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Chicken Mothers against decapentaplegic homolog 6(SMAD6),Mammalian cell
Code CSB-MP892952CH
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MFRSKRSGLV RRLWRSRVIP ERDGGDGNGQ SSERNATAVT AEGQRMAQPR RAQEGEGRPV RCCLFAERPG PELPPPPPPP PPGGASPPGP GGGEARSRLV LLERELKAVT YALLKRLKER SLHSLLQAVE SRGGTPGGCV LVARGELRLG AARRPPPHLL LGKLFRWPDL QHPAELKALC ECQSFGAADG PTVCCNPYHF SRLCGPESPP PPYSRLSPND EQKPLDLSDS TLSYTETEAT NSPNVTPGEF SDASTSPDAV KRSHWCNVAY WEHRTRVGRL YTVYEQSVSI FYDLPQGNGF CLGQLNLENR SETVRRTRSK IGYGILLSKE PDGVWAYNRS EHPIFVNSPT LDIPNCRTLI VRKVMPGYSI KVFDYEKSCL LQHTAELDYA DGPYDPNSVR ISFAKGWGPC YSRQFITSCP CWLEILLSNN R
Expression Region 1-431
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat

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