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Mothers against decapentaplegic homolog 6 is a protein in humans that is encoded by SMAD6 gene. Acts as a mediator of TGF-beta and BMP antiflammatory activity. Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory genes. May block the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor-activated SMAD1-binding. Binds to regulatory elements in target promoter regions.
SMAD6 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA009964 | SMAD6 Antibody |
Human,Mouse | WB,IHC,ELISA |
SMAD6 Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP021792MO CSB-EP021792MO CSB-BP021792MO CSB-MP021792MO |
Recombinant Mouse Mothers against decapentaplegic homolog 6(Smad6) |
Yeast E.coli Baculovirus Mammalian cell |
SMAD6 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP021792HU |
Recombinant Human Mothers against decapentaplegic homolog 6(SMAD6) |
Yeast |
SMAD6 Proteins for Gallus gallus (Chicken)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP892952CH CSB-EP892952CH CSB-BP892952CH CSB-MP892952CH |
Recombinant Chicken Mothers against decapentaplegic homolog 6(SMAD6) |
Yeast E.coli Baculovirus Mammalian cell |
SMAD6 ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-EL021792HU | Human Mothers against decapentaplegic homolog 6(SMAD6) ELISA kit |
serum, plasma, tissue homogenates, cell lysates | 3.9 pg/mL |
