Mothers against decapentaplegic homolog 6 is a protein in humans that is encoded by SMAD6 gene. Acts as a mediator of TGF-beta and BMP antiflammatory activity. Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory genes. May block the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor-activated SMAD1-binding. Binds to regulatory elements in target promoter regions.
SMAD6 Antibodies for Homo sapiens (Human)
|Code||Product Name||Species Reactivity||Application|
SMAD6 Proteins for Mus musculus (Mouse)
SMAD6 Proteins for Homo sapiens (Human)
SMAD6 Proteins for Gallus gallus (Chicken)
SMAD6 ELISA Kit for Homo sapiens (Human)
|Code||Product Name||Sample Types||Sensitivity|
|CSB-EL021792HU||serum, plasma, tissue homogenates, cell lysates||3.9 pg/mL|
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