Recombinant Human ATP-binding cassette sub-family A member 6(ABCA6) ,partial

Code CSB-YP839776HU
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Source Yeast
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Code CSB-EP839776HU
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Source E.coli
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Code CSB-EP839776HU-B
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP839776HU
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Source Baculovirus
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Code CSB-MP839776HU
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Source Mammalian cell
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Product Details

Purity >85% (SDS-PAGE)
Target Names ABCA6
Uniprot No. Q8N139
Alternative Names ABC transporter ABCA6; ABCA 6; ABCA6; ABCA6_HUMAN; ATP binding cassette A6; ATP binding cassette sub family A (ABC1) member 6; ATP binding cassette sub family A member 6; ATP-binding cassette sub-family A member 6; EST155051; FLJ43498
Species Homo sapiens (Human)
Protein Length Partial
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting
and FAQs
Protein FAQs
Storage Condition Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet Please contact us to get it.

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Target Background

Function
Probable transporter which may play a role in macrophage lipid transport and homeostasis.
Gene References into Functions
  1. A rare missense variant in ABCA6 (rs77542162, p.Cys1359Arg, frequency 0.034), found in a Dutch population, is predicted to be deleterious with respect to blood cholesterol levels. PMID: 25751400
  2. These data provide evidence for an essential role of FoxO proteins in the transcription of ABCA6 in human vascular endothelial cells. PMID: 24028821
Subcellular Location Golgi apparatus membrane; Multi-pass membrane protein.
Protein Families ABC transporter superfamily, ABCA family
Tissue Specificity Widely expressed with higher expression in liver.
Database Links

HGNC: 36

OMIM: 612504

KEGG: hsa:23460

STRING: 9606.ENSP00000284425

UniGene: Hs.709514

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Address
7505 Fannin St. Ste 610-312, Houston, TX 77054, USA
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