ABCA6 Antibody

Code CSB-PA988363
Size US$297 How to order?
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  • Western blot analysis of extracts from 293 cells, using ABCA6 antibody.
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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) ABCA6 Polyclonal antibody
Uniprot No. Q8N139
Target Names ABCA6
Alternative Names ABC transporter ABCA6 antibody; ABCA 6 antibody; ABCA6 antibody; ABCA6_HUMAN antibody; ATP binding cassette A6 antibody; ATP binding cassette sub family A (ABC1) member 6 antibody; ATP binding cassette sub family A member 6 antibody; ATP-binding cassette sub-family A member 6 antibody; EST155051 antibody; FLJ43498 antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Synthesized peptide derived from C-terminal of Human ABCA6.
Immunogen Species Homo sapiens (Human)
Clonality Polyclonal
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration It differs from different batches. Please contact us to confirm it.
Form Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Probable transporter which may play a role in macrophage lipid transport and homeostasis.
Gene References into Functions
  1. A rare missense variant in ABCA6 (rs77542162, p.Cys1359Arg, frequency 0.034), found in a Dutch population, is predicted to be deleterious with respect to blood cholesterol levels. PMID: 25751400
  2. These data provide evidence for an essential role of FoxO proteins in the transcription of ABCA6 in human vascular endothelial cells. PMID: 24028821
Subcellular Location Golgi apparatus membrane; Multi-pass membrane protein.
Protein Families ABC transporter superfamily, ABCA family
Tissue Specificity Widely expressed with higher expression in liver.
Database Links

HGNC: 36

OMIM: 612504

KEGG: hsa:23460

STRING: 9606.ENSP00000284425

UniGene: Hs.709514

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
Address
7505 Fannin St. Ste 610-312, Houston, TX 77054, USA
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