Recombinant Human G protein-activated inward rectifier potassium channel 2(KCNJ6),partial

Product Type Recombinant Protein
Uniprot No. P48051
Species Homo sapiens (Human)
Gene Names KCNJ6
Protein Names Recommended name: G protein-activated inward rectifier potassium channel 2 Short name= GIRK-2 Alternative name(s): BIR1 Inward rectifier K(+) channel Kir3.2 KATP-2 Potassium channel, inwardly rectifying subfamily J member 6
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Function This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
Involvement in disease Keppen-Lubinsky syndrome (KPLBS)
Subcellular Location Membrane, Multi-pass membrane protein
Protein Families Inward rectifier-type potassium channel (TC 1.A.2.1) family, KCNJ6 subfamily
Tissue Specificity Most abundant in cerebellum, and to a lesser degree in islets and exocrine pancreas.
Database Links

HGNC: 6267

OMIM: 600877

KEGG: hsa:3763

STRING: 9606.ENSP00000288309

UniGene: Hs.626242

Pathway Estrogen signaling pathway

Product Details for Different Expression Systems

Product Name Recombinant Human G protein-activated inward rectifier potassium channel 2(KCNJ6),partial,Yeast
Code CSB-YP012059HU1
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Protein Description Partial
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Human G protein-activated inward rectifier potassium channel 2(KCNJ6),partial,E.coli
Code CSB-EP012059HU1
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Protein Description Partial
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Human G protein-activated inward rectifier potassium channel 2(KCNJ6),partial,Baculovirus
Code CSB-BP012059HU1
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Protein Description Partial
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Human G protein-activated inward rectifier potassium channel 2(KCNJ6),partial,Mammalian cell
Code CSB-MP012059HU1
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Protein Description Partial
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat

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