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| Product Type | Recombinant Protein |
| Uniprot No. | P42701 |
| Species | Homo sapiens (Human) |
| Gene Names | IL12RB1 |
| Protein Names | Recommended name: Interleukin-12 receptor subunit beta-1 Short name= IL-12 receptor subunit beta-1 Short name= IL-12R subunit beta-1 Short name= IL-12R-beta-1 Short name= IL-12RB1 Alternative name(s): IL-12 receptor bet |
| Storage | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. |
| Notes | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
| Function | Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade. |
| Involvement in disease | Immunodeficiency 30 (IMD30) |
| Subcellular Location | Membrane, Single-pass type I membrane protein |
| Protein Families | Type I cytokine receptor family, Type 2 subfamily |
| Database Links |
HGNC: 5971 OMIM: 601604 KEGG: hsa:3594 STRING: 9606.ENSP00000403103 UniGene: Hs.567294 |
| Pathway |
Jak-STAT signaling pathway
Th1 and Th2 cell differentiation Th17 cell differentiation |
| Product Name | Recombinant Human Interleukin-12 receptor subunit beta-1(IL12RB1),partial,Yeast |
| Code | CSB-YP011588HU1 |
| Size | Pls inquiry other sizes |
| Source | Yeast |
| Purity | >85% (SDS-PAGE) |
| Tag Info | The following tags are available. N-terminal His-tagged Tag-Free The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
|
| Protein Description | Partial |
| Storage Buffer | Tris-based buffer,50% glycerol |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Product Name | Recombinant Human Interleukin-12 receptor subunit beta-1(IL12RB1),partial,E.coli |
| Code | CSB-EP011588HU1 |
| Size | Pls inquiry other sizes |
| Source | E.coli |
| Purity | >85% (SDS-PAGE) |
| Tag Info | The following tags are available. N-terminal His-tagged and C-terminal Myc-tagged N-terminal His-SUMO-tagged and C-terminal Myc-tagged N-terminal His-B2M-tagged and C-terminal Myc-tagged N-terminal His-GST-tagged and C-terminal Myc-tagged N-terminal His-tagged N-terminal His-SUMO-tagged N-terminal His-B2M-tagged N-terminal His-GST-tagged N-terminal GST-tagged Tag-Free The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
|
| Protein Description | Partial |
| Storage Buffer | Tris-based buffer,50% glycerol |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Product Name | Recombinant Human Interleukin-12 receptor subunit beta-1(IL12RB1),partial,Baculovirus |
| Code | CSB-BP011588HU1 |
| Size | Pls inquiry other sizes |
| Source | Baculovirus |
| Purity | >85% (SDS-PAGE) |
| Tag Info | The following tags are available. N-terminal His-tagged and C-terminal Myc-tagged N-terminal His-tagged Tag-Free The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
|
| Protein Description | Partial |
| Storage Buffer | Tris-based buffer,50% glycerol |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Product Name | Recombinant Human Interleukin-12 receptor subunit beta-1(IL12RB1),partial,Mammalian cell |
| Code | CSB-MP011588HU1 |
| Size | Pls inquiry other sizes |
| Source | Mammalian cell |
| Purity | >85% (SDS-PAGE) |
| Tag Info | The following tags are available. N-terminal His-tagged and C-terminal Myc-tagged N-terminal His-tagged Tag-Free The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
|
| Protein Description | Partial |
| Storage Buffer | Tris-based buffer,50% glycerol |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
IL12RB1 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA011588GA01HU | IL12RB1 Antibody | Human | ELISA,WB |
| CSB-PA006274 | IL12RB1 Antibody | Human | WB,ELISA |
| CSB-PA634409 | IL12RB1 Antibody | Human | ELISA,IHC |
| CSB-PA292651 | IL12RB1 Antibody | Human | ELISA,IHC |
| CSB-PA011588LB01HU | IL12RB1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA011588LC01HU | IL12RB1 Antibody, FITC conjugated | Human | ELISA |
| CSB-PA011588LD01HU | IL12RB1 Antibody, Biotin conjugated | Human | ELISA |
IL12RB1 Antibodies for Human
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA011588LA01HU | IL12RB1 Antibody | Human | ELISA, WB |
IL12RB1 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP011588HU CSB-EP011588HU CSB-BP011588HU CSB-MP011588HU |
Recombinant Human Interleukin-12 receptor subunit beta-1(IL12RB1) | Yeast E.coli Baculovirus Mammalian cell |
| CSB-CF011588HU | Recombinant Human Interleukin-12 receptor subunit beta-1(IL12RB1) | in vitro E.coli expression system |
IL12RB1 ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E17380h | Human Interleukin-12 receptor subunit beta-1 (IL12RB1/IL12R/IL12RB) ELISA kit | Request Information |
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