Recombinant Human L-dopachrome tautomerase (DCT),Partial

In Stock
Code CSB-EP006562HU
Product Type Recombinant Protein
Size US$1726Purchase it in Cusabio online store
(Shop online in the US. Customers outside the US,
please order from local distributors.)
Uniprot No. P40126
Lead Time 3-7 business days
Relevance Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA). Involved in regulating eumelanin and phaeomelanin levels.
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Storage Buffer Tris-based buffer,50% glycerol
Alias L-dopachrome Delta-isomerase Tyrosinase-related protein 2
Species Homo sapiens (Human)
Purity Greater than 90% as determined by SDS-PAGE.
Research Area others
Source E.coli
Gene Names DCT
Expression Region 24-472a
Tag Info N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged
Mol. Weight 71.3kDa
Protein Description Partial
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA)
Subcellular Location Melanosome membrane, Single-pass type I membrane protein, Melanosome
Protein Families Tyrosinase family
Database Links

HGNC: 2709

OMIM: 191275

KEGG: hsa:1638

UniGene: Hs.301865

Pathway Melanogenesis

Q&A and Customer Reviews


I was hoping you can supply more information about the expression of this protein in E.coli. Was it expressed as a soluble construct or from inclusion bodies with refolding? I am trying to express my own protein however I cannot get soluble protein and my protein does not work as well as the protein I bought from you. Are you able to help with this information? CSB-EP006562HU Recombinant Human L-dopachrome tautomerase (DCT)

Very nice to receive your inquiry. This protein is expressed from inclusion bodies with refolding.
You could also try to do inclusion bodies, then purify, and finally refold. The final buffer could refer to our datasheet.
Customer Reviews

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