DCT

The DCT protein plays a crucial role in the melanin synthesis pathway by converting dopachrome to 5,6-dihydroxyindole-2-carboxylic acid (DHICA), an intermediate in melanin biosynthesis. The enzymatic activity of DCT is essential for melanin pigmentation as DHICA serves as a critical precursor in the melanin synthesis process. Studying the Dct gene and its encoded protein contributes to understanding the mechanisms behind skin pigmentation and related diseases. Some skin conditions, like vitiligo, are associated with gene mutations or functional abnormalities in the melanin production process. Given DCT's pivotal role in melanin biosynthesis, it might serve as a potential therapeutic target for treating pigment-related diseases such as vitiligo. Understanding the role of the Dct gene and its encoded protein in melanin production is crucial for comprehending the mechanisms behind related diseases and developing treatment methods..

Popular Product

Recombinant Mouse L-dopachrome tautomerase (Dct), partial

Validated Data

SDS-PAGE

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.