Recombinant Human L-dopachrome tautomerase(DCT)

Code CSB-CF006562HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P40126
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Sequence QFPRVCMTVDSLVNKECCPRLGAESANVCGSQQGRGQCTEVRADTRPWSGPYILRNQDDRELWPRKFFHRTCKCTGNFAGYNCGDCKFGWTGPNCERKKPPVIRQNIHSLSPQEREQFLGALDLAKKRVHPDYVITTQHWLGLLGPNGTQPQFANCSVYDFFVWLHYYSVRDTLLGPGRPYRAIDFSHQGPAFVTWHRYHLLCLERDLQRLIGNESFALPYWNFATGRNECDVCTDQLFGAARPDDPTLISRNSRFSSWETVCDSLDDYNHLVTLCNGTYEGLLRRNQMGRNSMKLPTLKDIRDCLSLQKFDNPPFFQNSTFSFRNALEGFDKADGTLDSQVMSLHNLVHSFLNGTNALPHSAANDPIFVVLHSFTDAIFDEWMKRFNPPADAWPQELAPIGHNRMYNMVPFFPPVTNEELFLTSDQLGYSYAIDLPVSVEETPGWPTTLLVVMGTLVALVGLFVLLAFLQYRRLRKGYTPLMETHLSSKRYTEEA
Source in vitro E.coli expression system
Gene Names DCT
Protein Names Recommended name: L-dopachrome tautomerase Short name= DCT Short name= DT EC= 5.3.3.12 Alternative name(s): L-dopachrome Delta-isomerase Tyrosinase-related protein 2 Short name= TRP-2 Short name= TRP2
Expression Region 24-519
Tag Info 10xHis-SUMO-tag
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA)
Subcellular Location Melanosome membrane, Single-pass type I membrane protein, Melanosome
Protein Families Tyrosinase family
Database Links

HGNC: 2709

OMIM: 191275

KEGG: hsa:1638

UniGene: Hs.301865

Pathway Melanogenesis

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