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| Code | CSB-EP017459HU |
| MSDS | |
| Size | $224 |
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The expression region of this recombinant Human PARP11 covers amino acids 9-338. The theoretical molecular weight of the PARP11 protein is 41 kDa. The PARP11 protein was expressed in e.coli. The PARP11 coding gene included the N-terminal 6xHis tag, which simplifies the detection and purification processes of the recombinant PARP11 protein in following stages of expression and purification.
Poly [ADP-ribose] polymerase 11 (PARP11) is a member of the PARP family, which is involved in the regulation of various cellular processes, including DNA repair, genomic stability, and cell death. PARP enzymes catalyze the addition of ADP-ribose polymers to target proteins, a process known as poly(ADP-ribosyl)ation. PARP11, specifically, has been implicated in the regulation of immune responses. It is known to interact with components of the innate immune system and may play a role in modulating antiviral responses. Additionally, PARP11 has been associated with the endoplasmic reticulum-associated degradation (ERAD) pathway, suggesting a potential role in protein quality control. Research on PARP11 extends to understanding its precise molecular functions, its involvement in cellular processes beyond the immune response, and its potential implications in diseases.There are currently no reviews for this product.
