Code | CSB-EP018122HU |
MSDS | |
Size | $224 |
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Recombinant Human PLAUR is an E.coli cell-expressed protein (Full Length of Mature Protein). E.coli expression systems are popular because bacteria are easy to culture, grow fast and produce high yields of recombinant protein. Traditional strategies for Human PLAUR recombinant protein expression involve transforming the recombinant plasmid into the E. coli host. The cells were directly replicated, transcribed and translated, and IPTG was added to express the desired protein. Typically, the cells are then lysed to extract the expressed protein for subsequent purification. Also, many proteins become insoluble as inclusion bodies that are very difficult to recover, so mild conditions and subsequent cumbersome protein-refolding procedures are used to ensure the final provided protein is soluble.
PLAUR (also known as MO3 or UPAR) is a gene that encodes a protein named urokinase plasminogen activator surface receptor (short name is U-PAR or uPAR). The protein encoded by this gene, also called monocyte activation antigen Mo3 or CD87, is a glycosylphosphatidylinositol-anchored glycoprotein and cell surface receptor specific to the urokinase plasminogen activator (uPA) and is a promoter of plasmin activation. In addition to coagulation and fibrinolysis, uPAR is also involved in processes such as cell migration, cell cycle regulation, and cell adhesion, thereby participating in various disease processes such as tumour invasion and inflammation.There are currently no reviews for this product.
Can you confirm the following for this protein?
- Article contains human by-products
- Article contains animal by-products
- Article does not contain HIV / AIDS
- Article does not contain HCV / HBV
- Article does not contain any infectious materials