Recombinant Klebsiella pneumoniae Metallo-beta-lactamase type 2(blaNDM-1)

Code CSB-EP510513KBGa0
Product Type Recombinant Protein
Size
Uniprot No. C7C422
Image
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Storage Buffer Tris-based buffer,50% glycerol
Species Klebsiella pneumoniae
Purity Greater than 85% as determined by SDS-PAGE.
Sequence GEIRPTIGQQMETGDQRFGDLVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLVVDTAWTDDQTAQILNWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGMVAAQHSLTFAANGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLGDADTEHYAASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLR
Research Area Others
Source E.coli
Gene Names blaNDM-1
Expression Region 29-270aa
Tag Info N-terminal 6xHis-tagged
Mol. Weight 29.6 kDa
Protein Description Full Length of Mature Protein
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
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Function Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin.
Subcellular Location Periplasm
Protein Families Metallo-beta-lactamase superfamily, Class-B beta-lactamase family
Database Links

KEGG: ag:CAZ39946

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