Recombinant Mesocricetus auratus Protein disulfide-isomerase A6 (PDIA6)

Code CSB-YP017724MRG
MSDS
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Source Yeast
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Code CSB-EP017724MRG
MSDS
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Source E.coli
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Code CSB-EP017724MRG-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP017724MRG
MSDS
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Source Baculovirus
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Code CSB-MP017724MRG
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Uniprot No.
Alternative Names
PDIA6Protein disulfide-isomerase A6; EC 5.3.4.1; Protein disulfide isomerase P5
Species
Mesocricetus auratus (Golden hamster)
Expression Region
20-439
Target Protein Sequence
L YSSSDDVIEL TPSNFNREVI QSNSLWLVEF YAPWCGHCQR LTPEWKKAAT ALKDVVKVGA VDADKHQSLG GQYGVQGFPT IKIFGANKNK PEDYQGGRTG EAIVDAALSA LRQLVKDRLS GRSGGYSSGK QGRGDSSSKK DVIELTDDTF DKNVLDSDDV WMVEFYAPWC GHCKNLEPEW ATAATEVKEQ TKGKVKLAAV DATVNQVLAN RYGIRGFPTI KIFQKGEAPV DYDGGRTRSD IVSRALDLFS DNAPPPELLE IINEDVAKKM CEEHQLCVVA VLPHILDTGA ARNSYLEILL KLADKYKKKM WGWLWTEAGA QSELENALGI GGFGYPAMAR INARKMKFAL LKGSFSEQGI NEFLRELSFG RASTAPVGGG SFPAITAREP WDGRDGELPV EDDIDLSDVE LDDLEKDEL
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
May function as a chaperone that inhibits aggregation of misfolded proteins. Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling. May also regulate the UPR via the EIF2AK3 UPR sensor. Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin.
Subcellular Location
Endoplasmic reticulum lumen. Cell membrane. Melanosome.
Protein Families
Protein disulfide isomerase family
Tissue Specificity
Expressed most abundantly in lung and kidney, followed by heart, liver and brain.
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