Recombinant Mouse Protein OS-9 (Os9)

Code CSB-YP815653MO
MSDS
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Source Yeast
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Code CSB-EP815653MO
MSDS
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Source E.coli
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Code CSB-EP815653MO-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP815653MO
MSDS
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Source Baculovirus
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Code CSB-MP815653MO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Os9
Uniprot No.
Alternative Names
Os9; Protein OS-9
Species
Mus musculus (Mouse)
Expression Region
27-672
Target Protein Sequence
GVGS LNLEELSEMR YGIQILPLPV MGGQSQASDV VVVSSKYKQR YECRLPAGAI HFQREREEET PAYQGPGIPE LLSPMRDAPC LLKTKDWWTY EFCYGRHIQQ YHMEDSEIKG DVLYLGHYQS SFNWDDETAK ASKQHRLKRY HSQTYGNGSK CDLNGKPREA EVRFLCDEGA GISGDYIDRV DEPVSCSYVL TIRTSRLCPH PLLRPPASAA PQAILCHPAL QPDEYMAYLQ RQAESKQHEE KTTEEVQDTD RQVWSGSKAA GAPPKKEDVS PAKEEKESEL WKLQGPEEQA AAREEAQAGE QDLNHEAAAD PAPSPPNDFQ NNVQVKLIRS PADLIRLIEE LKAAEKGKPS VRREQPGDDT TEAPQREAEG TKAKGKDGEP PGLMEEEDGD DEEEEEEEEE DEEEQQLLGE FEKELEGMLL PSNRERLRSE VKAGMERELE NIIQETEKEL DPEGLRKESE REQAILALTS TLDKLIKRLQ ENQSPELVQK YKKRRVVPQK PPPSPHPTEE EPEHRVRVRV TKLRPGGPNR DLTVLEMNRE NPQLKQIEGL VTEVLEREGL TAEGKIEIKI VRPGAEGKEE DTRWLTDEDT RNLKEIFFNI LVQGAEEANK ERQRQSELES NYRRVWGSPG GEDTGDLDEF DF
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation. Possible targets include TRPV4.
Gene References into Functions
  1. Data suggest renal cell lines exhibit an OS9-mediated ERAD (endoplasmic reticulum-associated degradation) pathway that degrades Nkcc2/Slc12a1 (solute carrier family 12 member 1) prior to glycosylation/processing. PMID: 26721884
  2. The depletion of OS-9 in 3T3-L1 adipocytes impaired cell function in terms of triacylglycerol storage, and slightly influenced cell differentiation. PMID: 21523322
  3. OS-9 regulates the secretory transport of TRPV4 and appears to protect TRPV4 subunits from the precocious ubiquitination and ER-associated degradation. PMID: 17932042
Subcellular Location
Endoplasmic reticulum lumen.
Protein Families
OS-9 family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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