Purity
Greater than 90% as determined by SDS-PAGE.
Alternative Names
Mmp3; Stromelysin-1; SL-1; EC 3.4.24.17; EMS-2; Matrix metalloproteinase-3; MMP-3; Transin-1
Species
Mus musculus (Mouse)
Expression Region
104-477aa
Target Protein Sequence
PGSPKWRKSHITYRIVNYTPDLPRQSVDSAIEKALKVWEEVTPLTFSRISEGEADIMISFAVGEHGDFVPFDGPGTVLAHAYAPGPGINGDAHFDDDERWTEDVTGTNLFLVAAHELGHSLGLYHSAKAEALMYPVYKSSTDLSRFHLSQDDVDGIQSLYGTPTASPDVLVVPTKSNSLEPETSPMCSSTLFFDAVSTLRGEVLFFKDRHFWRKSLRTPEPEFYLISSFWPSLPSNMDAAYEVTNRDTVFIFKGNQFWAIRGHEELAGYPKSIHTLGLPATVKKIDAAISNKEKRKTYFFVEDKYWRFDEKKQSMEPGFPRKIAEDFPGVDSRVDAVFEAFGFLYFFSGSSQLEFDPNAKKVTHILKSNSWFNC
Note: The complete sequence including tag
sequence, target protein sequence and linker sequence could be provided upon request.
Protein Length
Full Length of Mature Protein
Tag Info
N-terminal 6xHis-tagged
Form
Liquid or Lyophilized powder
Note: We will preferentially ship the format that
we have in stock, however, if you have any special requirement for the format, please remark your
requirement when placing the order, we will prepare according to your demand.
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
Note: If you have any special requirement for the
glycerol content, please remark when you place the order.
If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer,
6% Trehalose.
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw
cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature
and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized
form is 12 months at -20°C/-80°C.
Lead Time
3-7 business days
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA
Please contact us to get it.
Description
The recombinant Mouse Mmp3 was expressed with the amino acid range of 104-477. The theoretical molecular weight of the Mmp3 protein is 46.2 kDa. This Mmp3 protein is produced using e.coli expression system. The Mmp3 gene fragment has been modified by fusing the N-terminal 6xHis tag, providing convenience in detecting and purifying the recombinant Mmp3 protein during the following stages.
The mouse Stromelysin-1, encoded by the Mmp3 gene, is a matrix metalloproteinase (MMP) that plays a key role in tissue remodeling and extracellular matrix degradation. It belongs to the zinc-dependent endopeptidase family and is involved in the proteolytic processing of various substrates within the extracellular matrix. Mmp3 is known for its ability to cleave components of the extracellular matrix, such as collagen, fibronectin, and proteoglycans. This activity is crucial for physiological processes like tissue repair, embryonic development, and immune response. Research on mouse Mmp3 spans various areas, including its involvement in arthritis, wound healing, and cancer progression. Understanding the regulation and function of Mmp3 provides insights into its role in normal physiological processes and its potential implications in pathological conditions.
