Recombinant Pig Fatty acid-binding protein, adipocyte (FABP4)

Code CSB-YP007945PI
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Source Yeast
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Code CSB-EP007945PI
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Source E.coli
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Code CSB-EP007945PI-B
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP007945PI
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Source Baculovirus
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Code CSB-MP007945PI
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
FABP4
Uniprot No.
Alternative Names
FABP4Fatty acid-binding protein; adipocyte; AP2; Adipocyte lipid-binding protein; ALBP; Adipocyte-type fatty acid-binding protein; A-FABP; AFABP; Fatty acid-binding protein 4
Species
Sus scrofa (Pig)
Expression Region
2-132
Target Protein Sequence
CDAFVGTWK LVSSENFDDY MKEVGVGFAT RKVAGMAKPN LIITVNGDMI TIRSESTFKN TEIAFKLGQE FDEVTADDRK VKSTITLDGG ALVQVQKWDG KTTTINRKIV DDKLVVECIM KGVTATRIYE RA
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus. Involved in the regulation of intramuscular fat accretion.
Gene References into Functions
  1. FABP4 gene expression level in adipose tissue was higher than in muscle. In contrast, FABP5 was expressed at low levels in adipocytes and muscle tissues. Low and moderate correlations between FABP4 and FABP5 gene expression were observed in muscle and in backfat, respectively. PMID: 29076225
  2. the A-FABP gene is strongly related to the development and function of intramuscular fat accretion in pigs. PMID: 23135696
  3. AFABP is significantly increased in coronary artery in-stent restenosis segments of both diabetic and nondiabetic minipigs. PMID: 23372061
  4. Thus A-FABP may be a candidate gene or a quantitative trait locus-linked gene associated with meat quality traits. PMID: 21846497
  5. Monitoring of posttransplant L-FABP plasma levels is a valuable new tool to quantify early the extent of parenchymal cell damage of non-heart-beating donors in liver transplantation. PMID: 15808662
  6. study suggests that FABP-4 protein content may be a valuable marker of lipid accretion PMID: 16612010
  7. A study of the mapping characteristics and relationship to body composition of FAT1 and FABP4 in swine is reported. PMID: 17032783
  8. regenerated coronary endothelial cells exhibit upregulation of adipocyte fatty acid binding protein (A-FABP) PMID: 17942849

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Subcellular Location
Cytoplasm. Nucleus.
Protein Families
Calycin superfamily, Fatty-acid binding protein (FABP) family
Tissue Specificity
Adipose tissue.
Database Links

KEGG: ssc:399533

UniGene: Ssc.1089

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