Recombinant Rat Prorelaxin 1 (Rln1), partial

Citations (1)

Code	CSB-YP019749RA
MSDS	MSDS Datasheet
Size	Pls inquire
Source	Yeast
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Code	CSB-EP019749RA
MSDS	MSDS Datasheet
Size	Pls inquire
Source	E.coli
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Code	CSB-EP019749RA-B
MSDS	MSDS Datasheet
Size	Pls inquire
Source	E.coli
Conjugate	Avi-tag Biotinylated E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code	CSB-BP019749RA
MSDS	MSDS Datasheet
Size	Pls inquire
Source	Baculovirus
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Code	CSB-MP019749RA
MSDS	MSDS Datasheet
Size	Pls inquire
Source	Mammalian cell
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Product Details
Citations
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

Rln1

Uniprot No.

P01347

Alternative Names

Rln1; Rln; Prorelaxin 1 [Cleaved into: Relaxin B chain; Relaxin A chain]

Species

Rattus norvegicus (Rat)

Expression Region

23-57

Target Protein Sequence

RVSEEWMD QVIQVCGRGY ARAWIEVCGA SVGRLAL

Protein Length

Partial

Tag Info

Tag type will be determined during the manufacturing process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Form

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Buffer before Lyophilization

Tris/PBS-based buffer, 6% Trehalose.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Troubleshooting and FAQs

Protein FAQs

Storage Condition

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Lead Time

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Datasheet

Please contact us to get it.

Citations

Effects of swimming exercise and RLN2 induction on relaxin levels, MMP-13, TGFβ expression in the pubic cartilage of pregnant rats I Oktaviani,Journal of Pharmacy & Pharmacognosy Research,2022

Customer Reviews and Q&A

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Target Background

Function

Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals.

Gene References into Functions

Relaxin-1 mRNA in the hearts of diabetic rats was significantly increased and that relaxin-3 mRNA expression at different time points was decreased. In addition, significant down-regulation of the mRNA expression of RXFP1 and RXFP3 was observed at 4 weeks after Streptozocin. PMID: 28776188
The digestive tract has been shown to express relaxin receptors; the hormone appears to exert site-specific effects acting at the neural or at the smooth muscle level, mainly by a nitric oxide-mediated mechanism. (Review) PMID: 28606038
We have shown that relaxin stimulates Sertoli cell proliferation through the activation of MEK/ERK1/2 and PI3K/AKT pathways. PMID: 24640565
The aim of the present study was to explore a role of relaxin at specific stages of spermatogenesis using a co-culture of rat Sertoli and germ cells. PMID: 24640566
Raxin is a mediator of the refractoriness of the mesangial cells to angiotensin II during pregnancy. PMID: 23207895
Data demonstrate a functional role for relaxin in mediating uterine artery compliance in pregnant rats, which may be necessary to maintain adequate uterine blood flow to the uterus and placenta. PMID: 22744867
A novel G-quadruplex in the relaxin gene, is reported. PMID: 22363579
Rln-1 was localized in the granulosa cells of the ovarian follicles, and immunoreactivity against Rln 1 was increased by orthodontic tooth movement in a time-dependent manner. PMID: 21410550
relaxin regulates fibroblast proliferation, differentiation, and collagen deposition and may have therapeutic potential in diseased states characterized by cardiac fibrosis. PMID: 15155573
role for relaxin in the systemic hemodynamic changes of pregnancy, as well as novel therapeutic potential for relaxin in modifying arterial stiffness and cardiac afterload. PMID: 15198972
High glucose concentration could stimulate the expression of endogenous relaxin. PMID: 19542742