Recombinant Rotavirus A Outer capsid glycoprotein VP7

Product Type Recombinant Protein
Uniprot No. A8D8S8
Species Rotavirus A (strain RVA/Cow/Canada/C486/1977/G6P6[1]) (RV-A)
Protein Names Recommended name: Outer capsid glycoprotein VP7
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Function Outer capsid protein involved in attachment and possibly entry into the host epithelial cell. It is subsequently lost, together with VP4, following virus entry into the host cell. The outer layer contains 780 copies of VP7, grouped as 260 trimers. Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors. In integrin-dependent strains, VP7 seems to essentially target the integrin heterodimers ITGAX/ITGB2 and ITGA5/ITGB3 at a postbinding stage, once the initial attachment by VP4 has been achieved (By similarity).
Subcellular Location Virion, Host endoplasmic reticulum lumen
Protein Families Rotavirus VP7 family

Product Details for Different Expression Systems

Product Name Recombinant Rotavirus A Outer capsid glycoprotein VP7,Mammalian cell
Code CSB-MP420195RIU
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence QNYGVNL PITGSMDTAY ANSTQSEPFL TSTLCLYYPV EASNEIADTE WKDTLSQLFL TKGWPTGSVY LKEYADIAAF SVEPQLYCDY NLVLMKYDST QELDMSELAD LILNEWLCNP MDITLYYYQQ TDEANKWISM GSSCTVKVCP LNTQTLGIGC LITNPDTFET VATTEKLVIT DVVDGVSHKL NVTTATCTIR NCKKLGPKEN VAVIQVGGAN ILDITADPTT TPQTERMMAI IWKKWWQVVY PVVDYVNQII QTMSKRSRSL NSSAFYYRV
Expression Region 34-309
Protein Description Full Length of Mature Protein
Storage Buffer Tris-based buffer,50% glycerol
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