Recombinant Xenopus laevis Suppressor of hairless protein homolog(rbpj) ,partial

Code CSB-YP835525XBE
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Source Yeast
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Code CSB-EP835525XBE
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Source E.coli
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Code CSB-EP835525XBE-B
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP835525XBE
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Source Baculovirus
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Code CSB-MP835525XBE
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Source Mammalian cell
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Product Details

Purity >85% (SDS-PAGE)
Target Names rbpj
Uniprot No. Q91880
Alternative Names rbpj; rbpsuh; suh; Suppressor of hairless protein homolog; X-Su(H)
Species Xenopus laevis (African clawed frog)
Expression Region 1-501
Target Protein Sequence MQPGIPKYTP SAIQLAPVVT GKFGERPQPK RLTREAMRNY LKERGDQTVL ILHAKVAQKS YGNEKRFFCP PPCVYLMGSG WKKKKEQMER DGCSEQESQP CAFIGIGNSE QEMQQLNLEG KNYCTAKTLY ISDSDKRKHF MLSVKMFYGN SDDIGVFLSK RIKVISKPSK KKQSLKNADL CIASGTKVAL FNRLRSQTVS TRYLHVEGGN FHASSQQWGA FYIHLLDDEE SEGEEFTVRD GYIHYGQTVK LVCSVTGMAL PRLIIRKVDK QTALLDADDP VSQLHKCAFY LKDTERMYLC LSQERIIQFQ ATPCPKEPNK EMINDGASWT IISTDKAEYT FYEGMGPINA PVTPVPVVES LQLNGGGDVA MLELTGQNFT PNLRVWFGDV EAETMYRCAE SMLCVVPDIS AFREGWRWVR QPVQVPVTLV RNDGVIYSTS LTFTYTPEPG PRPHCSAAGA ILRANSSLLA SNEPNTNSEG SYTNISTNSA NVTSSTAAVV S
Protein Length full length protein
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form Lyophilized powder
Buffer before Lyophilization Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting
and FAQs
Protein FAQs
Storage Condition Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet Please contact us to get it.

Target Data

Function Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes (By similarity). Required for the transcriptional activation of ESR1, suggesting that it is required during primary neurogenesis in embryos. Binds to the oxygen responsive element of COX4I2 and activates its transcription under hypoxia conditions (4% oxygen) (By similarity).
Gene References into Functions
  1. The study reports the identification and functional characterization of rbpj interacting and tubulin associated (RITA) (C12ORF52) as a novel rbpj/CBF-1-interacting protein. PMID: 21102556
  2. The results suggest that a cell-to-cell interaction via the Notch/Su(H) pathway has a significant role in the PGC migration by regulating cell motility. PMID: 20151992
Subcellular Location Nucleus, Cytoplasm
Protein Families Su(H) family
Database Links

KEGG: xla:399453

UniGene: Xl.12006

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