Code | CSB-RA440943A0HU |
Size | US$210 |
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Application | Recommended Dilution |
---|---|
WB | 1:500-1:5000 |
IHC | 1:50-1:200 |
CD55 is a GPI-anchored molecule found on leukocytes, erythrocytes, and serum-exposed stromal cells that accelerates the decay of the complement convertases C3 and C5. CD55 is involved in complement-independent processes and is hijacked by various viral and bacterial pathogens to increase cell adhesion and invasion in addition to acting as a complement regulator. CD55 has been identified as a critical host receptor for malaria parasite infection. CD55 also serves as a binding partner for CD97, whose expression is rapidly increased when T and B cells are activated. CD55 is associated with cancer, protein-losing enteropathy, and malaria, among other illnesses. CD55 loss causes complement hyperactivation, malabsorption, and angiopathic thrombosis in some cases of protein-losing enteropathy.
The recombinant CD55 antibody is a monoclonal antibody generated by cloning CD55 antibody genes into plasma vectors and transfecting vector clones into stable cell lines for production. For recombinant antibody generation, mammalian cell lines like CHO cells and HEK293 are commonly used. The recombinant CD55 antibody was purified using Affinity-chromatography. It has verified to detect CD55 protein from Human in the ELISA, WB, IHC.There are currently no reviews for this product.