Code | CSB-RA983477A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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FC | 1:50-1:200 |
The FPGS recombinant monoclonal antibody is generated through in vitro expression systems developed by cloning the DNA sequences of FPGS antibodies from immunoreactive rabbits. The immunogen employed in this process is a synthesized peptide derived from the human FPGS protein. Subsequently, the genes encoding the FPGS antibodies are inserted into plasmid vectors, and these recombinant plasmid vectors are transfected into host cells to facilitate antibody expression. The FPGS recombinant monoclonal antibody then undergoes affinity-chromatography purification and is rigorously tested for functionality in ELISA and FC applications. These tests confirm its reactivity with the human FPGS protein.
The main role of FPGS protein is to regulate and enhance the cellular uptake and utilization of folate by converting it into polyglutamate forms. This modification allows folate to be retained within cells, stored for future use, and optimally utilized in essential biochemical processes, including DNA synthesis, amino acid metabolism, and methylation reactions.
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