Code | CSB-RA271669A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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WB | 1:500-1:5000 |
IHC | 1:50-1:200 |
FURIN is a subtilisin-like proprotein convertase with diverse cellular functions. Furin has a well-known role in viral pathogenesis and efficiently cleaves polybasic or multi-basic sites such as those found in influenza virus subtype H5 and H7. Emerging evidence suggests that FURIN plays a critical role in the activation and infectivity of SARS-CoV-2. In SARS-CoV-2, structural studies have suggested that furin cleavage at the S1/S2 boundary primes the spike for an open conformation required for binding to the ACE2 entry receptor.
The generation of this recombinant FURIN antibody occurs in a series of steps: immunization, splenocytes & PBMC, single B cell sorting, mRNA extraction, RT-PCR & insert vector, expression, ELISA validation. And ELISA, WB, IHC was carried out Every step was performed under strict standards to ensure the researchers can have a recombinant FURIN antibody with premium quality.There are currently no reviews for this product.