Code | CSB-RA566370A0HU |
Size | US$210 |
Order now | |
Image |
|
Have Questions? | Leave a Message or Start an on-line Chat |
Application | Recommended Dilution |
---|---|
IHC | 1:50-1:200 |
The GAA recombinant monoclonal antibody is synthetically generated in vitro, starting with the extraction of GAA antibody genes from B cells isolated from immunoreactive rabbits. These GAA antibody genes are then amplified and cloned into suitable phage vectors, which are subsequently introduced into mammalian cell lines to enable the production of functional antibodies. Following this, the GAA recombinant monoclonal antibody undergoes affinity chromatography purification. This antibody shows good results in the detection of human GAA protein in ELISA and IHC applications.
Lysosomal alpha-glucosidase (GAA) is a crucial enzyme involved in the breakdown of glycogen within lysosomes. Its primary function is to hydrolyze glycogen into glucose, helping to maintain glucose homeostasis and prevent glycogen accumulation in various tissues. Dysfunction or deficiency of this enzyme can lead to serious health conditions, such as Pompe disease.
There are currently no reviews for this product.