GP Recombinant Monoclonal Antibody

Datasheet

Code	CSB-RA810349MA1CSC
Size	US$210
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Image	The Binding Activity of CCHFV GP with Anti-GP recombinant antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized CCHFV GP (CSB-MP810349CSC2) at 2 μg/mL can bind Anti-GP recombinant antibody. The EC₅₀ is 3.136-3.585 ng/mL. The purity of GP was greater than 95% as determined by SEC-HPLC
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Target Background

Product Details

Uniprot No.

Q8JSZ3

Target Names

Alternative Names

GP; Envelopment polyprotein; M polyprotein

Species Reactivity

Crimean-Congo hemorrhagic fever virus

Immunogen

Recombinant Crimean-Congo hemorrhagic fever virus GP protein

Immunogen Species

Crimean-Congo hemorrhagic fever virus (strain Nigeria/IbAr10200/1970) (CCHFV)

Conjugate

Non-conjugated

Clonality

Monoclonal

Isotype

hIgG1

Clone No.

4A5

Purification Method

Affinity-chromatography

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Recommended Dilution

Application	Recommended Dilution
ELISA	1:5000-1:50000

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Glycoprotein C and glycoprotein N interact with each other and are present at the surface of the virion. They are able to attach the virion to host cell receptors. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Also promotes fusion of viral membrane with host endosomal membrane after endocytosis of the virion.

Subcellular Location

[Glycoprotein C]: Virion membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Host endoplasmic reticulum membrane; Single-pass type I membrane protein.; [Glycoprotein N]: Virion membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein.

Protein Families

Nairovirus envelope glycoprotein family

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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