Code | CSB-RA010242A0HU |
Size | US$210 |
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Application | Recommended Dilution |
---|---|
WB | 1:500-1:5000 |
IHC | 1:50-1:200 |
IP | 1:200-1:1000 |
HDAC6 antibody CSB-RA010242A0HU is a recombinant monoclonal antibody belonging to rabbit IgG. Its production procedures include: the acquisition of the HDAC6 monoclonal antibody using the synthesized peptide derived from the human HDAC6 immunizes animals; the determination of DNA sequence of the HDAC6 monoclonal antibody; the clone of the DNA sequence into the plasmid and subsequent transfection into cell lines for expression. This HDAC6 antibody underwent purification using affinity-chromatography. It has been tested in multiple applications, including ELISA, WB, IHC, and IP. It is reactive with the human HDAC6 protein.
Its target protein HDAC6 is a unique histone deacetylase that deacetylates histones and inhibits transcription of related genes. Endogenous HDAC6 is localized to the cytoplasm and becomes a tubulin deacetylase when binding to microtubules. HDAC6 contains a zinc finger domain, which may be involved in the regulation of ubiquitination degradation.
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