Code | CSB-RA248028A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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IHC | 1:50-1:200 |
The PAX8 recombinant monoclonal antibody is produced through in vitro expression systems, involving the cloning of PAX8 antibody DNA sequences from immunoreactive rabbits. The immunogen used is a synthesized peptide derived from the human PAX8 protein. Subsequently, the genes encoding the PAX8 antibodies are incorporated into plasmid vectors, and these recombinant plasmid vectors are transfected into host cells to enable antibody expression. The PAX8 recombinant monoclonal antibody then undergoes affinity-chromatography purification and is extensively tested for functionality in ELISA and IHC applications, displaying reactivity with the human PAX8 protein during these assessments.
PAX8 is a transcription factor that is critical for the development and function of various tissues and organs, including the thyroid gland, kidneys, female reproductive system, and potentially other tissues. Its role in regulating gene expression is essential for tissue differentiation, development, and function.
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