Code | CSB-RA568053A0HU |
Size | US$210 |
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Application | Recommended Dilution |
---|---|
WB | 1:500-1:5000 |
FC | 1:20-1:200 |
PDCD6IP, also called ALIX, is involved in protein transport and trafficking in the cells. PDCD6IP associates with lysobisphosphatidic acid at the late endosome membrane and subunits of the ESCRT machinery to promote membrane abscission events such as intraluminal endosomal vesicle formation, exosome secretion, and enveloped virus budding. intraluminal vesicle formation, exosome biogenesis, and viral budding. PDCD6IP also controls the spatial distribution of late endosomes, likely via interactions with the actin-remodeling protein CTTN (cortactin). It also participates in numerous biological processes including programmed neuronal death, virus egress, cytokinesis, and membrane repair.
The recombinant PDCD6IP antibody was prepared by obtaining the antibody genes, cloning the genes into a plasma vector to construct vector clone, transfecting the vector clone into a mammalian cell line for transient expression, and purifying the antibody by Affinity-chromatography. This recombinant PDCD6IP antibody has been verified to detect the PDCD6IP protein from Human, Rat in the ELISA, WB, FC.There are currently no reviews for this product.