Code | CSB-RA067358A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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IF | 1:50-1:200 |
FC | 1:50-1:200 |
The USP22 recombinant monoclonal antibody is synthetically produced in vitro using a systematic approach. Initially, USP22 antibody genes are extracted from B cells isolated from immunoreactive rabbits. These genes undergo amplification and are cloned into suitable phage vectors, which are subsequently introduced into mammalian cell lines to facilitate the production of functional antibodies in significant quantities. The resulting USP22 recombinant monoclonal antibody is subjected to affinity chromatography purification. After rigorous verification, the antibody can be used in ELISA, IF, and FC applications, allowing for precise detection of human USP22 protein.
USP22 is a multifunctional protein that plays a crucial role in epigenetic regulation by deubiquitinating histones and modulating chromatin structure. Its activities impact gene expression, cell cycle control, stem cell maintenance, DNA repair, and various aspects of development. Dysregulation of USP22 can have significant implications for diseases, including cancer.
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