Code | CSB-RA620753A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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IHC | 1:50-1:200 |
FC | 1:50-1:200 |
The process of creating the WDR5 recombinant monoclonal antibody begins by obtaining the WDR5 antibody genes. These genes are then introduced into suitable host cells, which are cultured for synthesizing WDR5 antibodies using a cell-based expression and translation system. This method offers several advantages, including significantly improving the purity and stability of the resulting WDR5 recombinant monoclonal antibodies, as well as enhancing their affinity and specificity. Following synthesis, the WDR5 recombinant monoclonal antibody undergoes purification through affinity chromatography. Subsequently, it undergoes thorough testing via various assays, including ELISA, IHC, and FC. This antibody specifically recognizes the human WDR5 protein.
WDR5 is a critical component of protein complexes involved in epigenetic regulation, chromatin remodeling, and gene expression control. Its primary function is to promote histone methylation at specific gene promoters, thereby regulating gene activation and repression. Proper WDR5-mediated regulation is crucial for normal development, cellular differentiation, and maintaining the balance of gene expression in health and disease.
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