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CHOK1/Human CLDN9 Stable Cell Line

Code CSB-SC005511HU3
Size 1 vial contains approximately 5x106 cells in 1 ml
Price $5000
Image
  • Untransfected CHO-K1 cells (green line) and transfected Human CLDN9 CHO-K1 stable cells (red line) were stained with anti-CLDN6/9 antibody(CSB-RA005508MA1HU) (2µg/1*106cells), washed and then followed by APC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
  • Untransfected CHO-K1 cells (green line) and transfected Human CLDN9 CHO-K1 stable cells (red line) were stained with anti-CLDN6/9 antibody(CSB-RA005508MA3HU) (2µg/1*106cells), washed and then followed by APC-conjugated anti-Mouse IgG Fc antibody and analyzed with flow cytometry.
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Product Details

Uniprot No.
O95484
Growth Properties
Adherent
Selection Marker
Puromycin
Culture Medium
F-12K + 10% FBS + 8 μg/ml Puromycin
Alternative Names
CLDN9
Tag Info
Tag-Free
Buffer
35% FBS + 55% F-12K + 10% DMSO
Tested Applications
Binding assay by FACS and cell based ELISA.
Storage
Frozen in liquid nitrogen or -80°C
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
(From Uniprot)
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.; (Microbial infection) Acts as a receptor for hepatitis C virus (HCV) entry into hepatic cells.
Gene References into Functions
  1. CLDN9 may be an important biomarker for invasive pituitary oncocytomas. PMID: 25281028
  2. Claudins 6, 7, and 9 expressions are closely related to gastric carcinogenesis. PMID: 19960275
  3. Mouse studies suggest that claudin-9 deficiency may cause hearing loss not only in mice but also in humans. PMID: 19696885
  4. Residues N38 and V45 in the first extracellular loop (EL1) of CLDN9 are necessary for HCV entry. PMID: 17804490
  5. CLDN9, clustered with CLDN6 at human chromosome 16p13.3, is a four-transmembrane protein with WWCC motif, defined by W-X(17-22)-W-X(2)-C-X(8-10)-C. PMID: 12736707

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Subcellular Location
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
Protein Families
Claudin family
Tissue Specificity
Expressed in the liver, in peripheral blood mononuclear cells and hepatocarcinoma cell lines.
Database Links

HGNC: 2051

OMIM: 615799

KEGG: hsa:9080

STRING: 9606.ENSP00000398017

UniGene: Hs.296949

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