Recombinant Chicken Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit(DDOST)

Code CSB-CF006594CH
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P48440
Storage Buffer Tris-based buffer,50% glycerol
Species Gallus gallus (Chicken)
Sequence GPRSLVLLENLNLRDTHSLFFRSLADRGFELTFRTADDAGLSLIKYGEFLYDNLIIFSPSIEDFGGNINVETITAFIDGGGSVLVAASSDIGDPLRELGSECGIEFDEERTAVIDHHNYDISDPGQHTLIVADAENLLKAPTIVGKKALNPILFRGVGMVADPDNPLVLDILTGSSTSYSFFPDKPITQYPHAVGKNTLLIAGLQARNNARVVFSGSLDFFSDAFFSSAVQKAAPGSKRYSQTGNYELAVALSRWVFKEEGVLRVGAVSHHRVGELAPPNAYTVTDLVEYSIVIEKLSDGKWIPFDGDDIQLEFVRIDPFVRTFLKRNGGKYSVQFKLPDVYGVFQFKVDYNRLGYTHLYSSTQVSVRPLQHTQYERFIPSAYPYYAGAFSMMVGLFMFSIVFLHMKEKEKSD
Source in vitro E.coli expression system
Gene Names DDOST
Protein Names Recommended name: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit Short name= DDOST 48 kDa subunit Short name= Oligosaccharyl transferase 48 kDa subunit EC= 2.4.1.119 Alternative name(s): OST 50 kDa subunit
Expression Region 1-413
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Required for the assembly of both SST3A- and SS3B-containing OST complexes. Required for efficient N-glycosylation.
Subcellular Location Endoplasmic reticulum, Endoplasmic reticulum membrane, Single-pass type I membrane protein
Protein Families DDOST 48 kDa subunit family
Database Links

STRING: 9031.ENSGALP00000038313

UniGene: Gga.13565

Pathway Protein processing in endoplasmic reticulum

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