Recombinant Cricetulus longicaudatus Heparan sulfate 2-O-sulfotransferase 1(HS2ST1)

Code CSB-CF010746DXV
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. O08889
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Species Cricetulus longicaudatus (Long-tailed dwarf hamster) (Chinese hamster)
Sequence MGLLRIMMPPKLQLLAVVAFAVAMLFLENQIQKLEESRAKLERAIARHEVREIEQRHTMDGPRQDAAVDEEEDIVIIYNRVPKTASTSFTNIAYDLCAKNRYHVLHINTTKNNPVMSLQDQVRFVKNITTWNEMKPGFYHGHISYLDFAKFGVKKKPIYINVIRDPIERLVSYYYFLRFGDDYRPGLRRRKQGDKKTFDECVAEGGSDCAPEKLWLQIPFFCGHSSECWNVGSRWAMDQAKYNLINEYFLVGVTEELEDFIMLLEAALPRFFRGATDLYRTGKKSHLRKTTEKKLPTKQTIAKLQQSDIWKMENEFYEFALEQFQFIRAHAVREKDGDLYILAQNFFYEKIYPKSN
Source in vitro E.coli expression system
Gene Names HS2ST1
Protein Names Recommended name: Heparan sulfate 2-O-sulfotransferase 1 Short name= 2-O-sulfotransferase Short name= 2OST EC= 2.8.2.-
Expression Region 1-356
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS). 2-O-sulfation within HS, particularly of iduronate residues, is essential for HS to participate in a variety of high-affinity ligand-binding interactions and signaling processes. Mediates 2-O-sulfation of both L-iduronyl and D-glucuronyl residues (By similarity).
Subcellular Location Golgi apparatus membrane, Single-pass type II membrane protein
Protein Families Sulfotransferase 3 family

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